Targeting tumor glycans for cancer therapy: successes, limitations, and perspectives

N Berois, A Pittini, E Osinaga - Cancers, 2022 - mdpi.com
Simple Summary Aberrant glycosylation is a common feature of many cancers, and it plays
crucial roles in tumor development and biology. Cancer progression can be regulated by …

Glycan gimmickry by parasitic helminths: a strategy for modulating the host immune response?

I Van Die, RD Cummings - Glycobiology, 2010 - academic.oup.com
Parasitic helminths (worms) co-evolved with vertebrate immune systems to enable long-term
survival of worms in infected hosts. Among their survival strategies, worms use their glycans …

Mucin-Type O-Glycosylation in Invertebrates

E Staudacher - Molecules, 2015 - mdpi.com
O-Glycosylation is one of the most important posttranslational modifications of proteins. It
takes part in protein conformation, protein sorting, developmental processes and the …

Glycans in the roles of parasitological diagnosis and host–parasite interplay

CDM Veríssimo, C Graeff-Teixeira, MK Jones… - Parasitology, 2019 - cambridge.org
The investigation of the glycan repertoire of several organisms has revealed a wide variation
in terms of structures and abundance of glycan moieties. Among the parasites, it is possible …

How tapeworms interact with cancers: a mini-review

M Schreiber, V Vajs, P Horák - PeerJ, 2024 - peerj.com
Cancer is one of the leading causes of death, with an estimated 19.3 million new cases and
10 million deaths worldwide in 2020 alone. Approximately 2.2 million cancer cases are …

Characterization of the N-glycans of female Angiostrongylus cantonensis worms

CM Veríssimo, AL Morassutti, M von Itzstein… - Experimental …, 2016 - Elsevier
Glycoconjugates play a crucial role in the host-parasite relationships of helminthic infections,
including angiostrongyliasis. It has previously been shown that the antigenicity of proteins …

Increased accumulation of regulatory granulocytic myeloid cells in mannose receptor C type 1-deficient mice correlates with protection in a mouse model of …

PK Mishra, EG Morris, JA Garcia… - Infection and …, 2013 - Am Soc Microbiol
Neurocysticercosis (NCC) is a central nervous system (CNS) infection caused by the
metacestode stage of the parasite Taenia solium. During NCC, the parasites release …

Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region

JGM Bolscher, J Brevoord, K Nazmi, T Ju… - Carbohydrate …, 2010 - Elsevier
Incomplete or aberrant glycosylation leading to Tn antigen (GalNAcα1-Ser/Thr) expression
on human glycoproteins is strongly associated with human pathological conditions …

Glycomics in unraveling glycan-driven immune responses by parasitic helminths

I van Die, RD Cummings - Handbook of glycomics, 2010 - Elsevier
Publisher Summary Helminths are multicellular eukaryotes that have a glycosylation
potential resembling mammalian glycosylation in some ways. They synthesize Nand …

[PDF][PDF] Carcinogenicity and Anti-tumoral Effect of Parasites: A Review Study

T Elmi, M Akbariqomi, F Khanabadi… - Journal of Military …, 2023 - militarymedj.bmsu.ac.ir
In endemic areas, some parasitic infections may be related to cancer induction or induction
of immune responses against cancer. In some cases, parasites cause disease in their host …