Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease

X Wang, W Huang, L Su, Y Xing, F Jessen… - Molecular …, 2020 - Springer
Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the
Alzheimer's disease (AD) continuum. Investigating populations with SCD is important for …

Brain glucose transporters: role in pathogenesis and potential targets for the treatment of Alzheimer's disease

L Szablewski - International Journal of Molecular Sciences, 2021 - mdpi.com
The most common cause of dementia, especially in elderly people, is Alzheimer's disease
(AD), with aging as its main risk factor. AD is a multifactorial neurodegenerative disease …

Subjective cognitive decline in cognitively normal elders from the community or from a memory clinic: differential affective and imaging correlates

A Perrotin, R La Joie, V de La Sayette, L Barré… - Alzheimer's & …, 2017 - Elsevier
Introduction Subjective cognitive decline (SCD) could indicate preclinical Alzheimer's
disease, but the existing literature is confounded by heterogeneous approaches to studying …

[HTML][HTML] Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease

L Bonfili, V Cecarini, O Gogoi, S Berardi… - Neurobiology of …, 2020 - Elsevier
Cerebral glucose homeostasis deregulation has a role in the pathogenesis and the
progression of Alzheimer's disease (AD). Current therapies delay symptoms without …

Glucose metabolism in the right middle temporal gyrus could be a potential biomarker for subjective cognitive decline: a study of a Han population

QY Dong, TR Li, XY Jiang, XN Wang, Y Han… - Alzheimer's Research & …, 2021 - Springer
Introduction Subjective cognitive decline (SCD) represents a cognitively normal state but at
an increased risk for developing Alzheimer's disease (AD). Recognizing the glucose …

[HTML][HTML] Gut microbiota is an impact factor based on the brain-gut axis to alzheimer's disease: A systematic review

B Zou, J Li, RX Ma, XY Cheng, RY Ma, TY Zhou… - Aging and …, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a degenerative disease of the central nervous system. The
pathogenesis of AD has been explained using cholinergic, β-amyloid toxicity, tau protein …

Selection of the optimal intensity normalization region for FDG-PET studies of normal aging and Alzheimer's disease

S Nugent, E Croteau, O Potvin, CA Castellano… - Scientific reports, 2020 - nature.com
The primary method for measuring brain metabolism in humans is positron emission
tomography (PET) imaging using the tracer 18F-fluorodeoxyglucose (FDG). Standardized …

Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture

W Liu, P Zhuo, L Li, H Jin, B Lin, Y Zhang… - Free Radical Biology …, 2017 - Elsevier
An essential feature of Alzheimer's disease (AD) is implicated in brain energy metabolic
impairment that is considered underlying pathogenesis of cognitive impairment. Therefore …

Reduced cerebral glucose uptake in an Alzheimer's rat model with glucose-weighted chemical exchange saturation transfer imaging

P Chen, Z Shen, Q Wang, B Zhang… - Frontiers in Aging …, 2021 - frontiersin.org
A correlation between the abnormal cerebral glucose metabolism and the progression of
Alzheimer's disease (AD) has been found in previous studies, suggesting that glucose …

The role of microRNA-34 family in Alzheimer's disease: A potential molecular link between neurodegeneration and metabolic disorders

M Bazrgar, P Khodabakhsh, M Prudencio… - Pharmacological …, 2021 - Elsevier
Growing evidence indicates that overexpression of the microRNA-34 (miR-34) family in the
brain may play a crucial role in Alzheimer's disease (AD) pathogenesis by targeting and …