Mitochondrial management of reactive oxygen species
Mitochondria in aerobic eukaryotic cells are both the site of energy production and the
formation of harmful species, such as radicals and other reactive oxygen species, known as …
formation of harmful species, such as radicals and other reactive oxygen species, known as …
Vitamin C and immune cell function in inflammation and cancer
Vitamin C (ascorbate) is maintained at high levels in most immune cells and can affect many
aspects of the immune response. Intracellular levels generally respond to variations in …
aspects of the immune response. Intracellular levels generally respond to variations in …
Connections between TET proteins and aberrant DNA modification in cancer
DNA methylation has been linked to aberrant silencing of tumor suppressor genes in cancer,
and an imbalance in DNA methylation–demethylation cycles is intimately implicated in the …
and an imbalance in DNA methylation–demethylation cycles is intimately implicated in the …
[HTML][HTML] Vitamin C: From nutrition to oxygen sensing and epigenetics
T Kietzmann - Redox Biology, 2023 - Elsevier
Vitamin C is unbeatable-at least when it comes to sales. Of all the vitamin preparations,
those containing vitamin C sell best. This is surprising because vitamin C deficiency is …
those containing vitamin C sell best. This is surprising because vitamin C deficiency is …
Vitamin C in stem cell biology: impact on extracellular matrix homeostasis and epigenetics
CD′ Aniello, F Cermola, EJ Patriarca… - Stem cells …, 2017 - Wiley Online Library
Transcription factors and signaling molecules are well‐known regulators of stem cell identity
and behavior; however, increasing evidence indicates that environmental cues contribute to …
and behavior; however, increasing evidence indicates that environmental cues contribute to …
Glucose metabolism and dynamics of facilitative glucose transporters (GLUTs) under the influence of heat stress in dairy cattle
Z Abbas, A Sammad, L Hu, H Fang, Q Xu, Y Wang - Metabolites, 2020 - mdpi.com
Heat stress is one of the main threats to dairy cow production; in order to resist heat stress,
the animal exhibits a variety of physiological and hormonal responses driven by complex …
the animal exhibits a variety of physiological and hormonal responses driven by complex …
Vitamin C as a Modulator of the Response to Cancer Therapy
W Blaszczak, W Barczak, J Masternak, P Kopczyński… - Molecules, 2019 - mdpi.com
Ascorbic acid (vitamin C) has been gaining attention as a potential treatment for human
malignancies. Various experimental studies have shown the ability of pharmacological …
malignancies. Various experimental studies have shown the ability of pharmacological …
Targeting reactive oxygen species capacity of tumor cells with repurposed drug as an anticancer therapy
J Wang, D Sun, L Huang, S Wang… - Oxidative medicine and …, 2021 - Wiley Online Library
Accumulating evidence shows that elevated levels of reactive oxygen species (ROS) are
associated with cancer initiation, growth, and response to therapies. As concentrations …
associated with cancer initiation, growth, and response to therapies. As concentrations …
Neurobiology of vitamin C: Expanding the focus from antioxidant to endogenous neuromodulator
SJ Ballaz, GV Rebec - Pharmacological research, 2019 - Elsevier
Ascorbic acid (AA) is a water-soluble vitamin (C) found in all bodily organs. Most mammals
synthesize it, humans are required to eat it, but all mammals need it for healthy functioning …
synthesize it, humans are required to eat it, but all mammals need it for healthy functioning …
Glucose transport and transporters in the endomembranes
B Lizák, A Szarka, Y Kim, K Choi, CE Németh… - International Journal of …, 2019 - mdpi.com
Glucose is a basic nutrient in most of the creatures; its transport through biological
membranes is an absolute requirement of life. This role is fulfilled by glucose transporters …
membranes is an absolute requirement of life. This role is fulfilled by glucose transporters …