[HTML][HTML] Better epitope discovery, precision immune engineering, and accelerated vaccine design using immunoinformatics tools
AS De Groot, L Moise, F Terry, AH Gutierrez… - Frontiers in …, 2020 - frontiersin.org
Computational vaccinology includes epitope mapping, antigen selection, and immunogen
design using computational tools. Tools that facilitate the in silico prediction of immune …
design using computational tools. Tools that facilitate the in silico prediction of immune …
An overview of in silico vaccine design against different pathogens and cancer
K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …
Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy
G Richard, MF Princiotta, D Bridon… - Expert Review of …, 2022 - Taylor & Francis
Introduction The field of cancer therapy has undergone a major transformation in less than a
decade due to the introduction of checkpoint inhibitors, the advent of next generation …
decade due to the introduction of checkpoint inhibitors, the advent of next generation …
[HTML][HTML] Q fever immunology: the quest for a safe and effective vaccine
Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …
[HTML][HTML] Q fever vaccine development: current strategies and future considerations
CM Long - Pathogens, 2021 - mdpi.com
Q fever is a zoonotic disease caused by the intracellular pathogen Coxiella burnetii. This
disease typically manifests as a self-limiting, febrile illness known as acute Q fever. Due to …
disease typically manifests as a self-limiting, febrile illness known as acute Q fever. Due to …
Engineering Protein Nanoparticles Functionalized with an Immunodominant Coxiella burnetii Antigen to Generate a Q Fever Vaccine
Coxiella burnetii is the causative agent of Q fever, for which there is yet to be an FDA-
approved vaccine. This bacterial pathogen has both extra-and intracellular stages in its life …
approved vaccine. This bacterial pathogen has both extra-and intracellular stages in its life …
[HTML][HTML] Genome-wide epitope mapping across multiple host species reveals significant diversity in antibody responses to Coxiella burnetii vaccination and infection
E Bach, SF Fitzgerald, SE Williams-MacDonald… - Frontiers in …, 2023 - frontiersin.org
Coxiella burnetii is an important zoonotic bacterial pathogen of global importance, causing
the disease Q fever in a wide range of animal hosts. Ruminant livestock, in particular sheep …
the disease Q fever in a wide range of animal hosts. Ruminant livestock, in particular sheep …
Diphtheria Toxoid Particles as Q Fever Vaccine
There is an unmet need for a stable and nonreactogenic vaccine against the bioterrorism
agent, Coxiella burnetii, causing Q fever. Here a safe, effective, and non‐reactogenic Q fever …
agent, Coxiella burnetii, causing Q fever. Here a safe, effective, and non‐reactogenic Q fever …
Current approaches for the detection of Coxiella burnetii infection in humans and animals
Q fever (coxiellosis), caused by Coxiella burnetii, is an emerging or re-emerging zoonotic
disease of public health significance and with worldwide distribution. As a causal agent of …
disease of public health significance and with worldwide distribution. As a causal agent of …
[HTML][HTML] Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity
T cell-mediated immunity plays a central role in the control and clearance of intracellular
Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel …
Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel …