Brain dysfunction in COVID‐19 and CAR‐T therapy: cytokine storm‐associated encephalopathy
Objective Many neurological manifestations are associated with COVID‐19, including a
distinct form of encephalopathy related to cytokine storm, the acute systemic inflammatory …
distinct form of encephalopathy related to cytokine storm, the acute systemic inflammatory …
[HTML][HTML] Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation
COVID survivors frequently experience lingering neurological symptoms that resemble
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …
[HTML][HTML] Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
Background Dementia-like cognitive impairment is an increasingly reported complication of
SARS-CoV-2 infection. However, the underlying mechanisms responsible for this …
SARS-CoV-2 infection. However, the underlying mechanisms responsible for this …
[HTML][HTML] CSF biomarkers in COVID-19 associated encephalopathy and encephalitis predict long-term outcome
M Guasp, G Muñoz-Sánchez… - Frontiers in …, 2022 - frontiersin.org
Patients with coronavirus disease 2019 (COVID-19) frequently develop acute
encephalopathy and encephalitis, but whether these complications are the result from viral …
encephalopathy and encephalitis, but whether these complications are the result from viral …
[HTML][HTML] Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain
A Fernández-Castañeda, P Lu, AC Geraghty, E Song… - BioRxiv, 2022 - ncbi.nlm.nih.gov
Abstract Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
infection frequently experience lingering neurological symptoms, including impairment in …
infection frequently experience lingering neurological symptoms, including impairment in …
Viral antigen and inflammatory biomarkers in cerebrospinal fluid in patients with COVID-19 infection and neurologic symptoms compared with control participants …
A Edén, A Grahn, D Bremell, A Aghvanyan… - JAMA network …, 2022 - jamanetwork.com
Importance Neurologic symptoms are common in COVID-19, but the central nervous system
(CNS) pathogenesis is unclear, and viral RNA is rarely detected in cerebrospinal fluid (CSF) …
(CNS) pathogenesis is unclear, and viral RNA is rarely detected in cerebrospinal fluid (CSF) …
[HTML][HTML] Emerging roles of type-I interferons in neuroinflammation, neurological diseases, and long-haul COVID
Interferons (IFNs) are pleiotropic cytokines originally identified for their antiviral activity. IFN-
α and IFN-β are both type I IFNs that have been used to treat neurological diseases such as …
α and IFN-β are both type I IFNs that have been used to treat neurological diseases such as …
Cerebrospinal fluid in COVID-19 neurological complications: Neuroaxonal damage, anti-SARS-Cov2 antibodies but no evidence of cytokine storm
Objective To study in cerebrospinal fluid (CSF) of COVID-19 subjects if a “cytokine storm” or
neuroinflammation are implicated in pathogenesis of neurological complications. Methods …
neuroinflammation are implicated in pathogenesis of neurological complications. Methods …
[HTML][HTML] Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers
Background The benefit of immune checkpoint inhibitors (ICIs) in patients with
leptomeningeal metastases (LMM) is unknown. Methods We undertook a phase II trial of …
leptomeningeal metastases (LMM) is unknown. Methods We undertook a phase II trial of …