In epithelial cancers, cells must invade through basement membranes (BMs) to metastasize.
The BM, a thin layer of extracellular matrix underlying epithelial and endothelial tissues, is …

The N‐end rule relates the regulation of the in vivo half‐life of a protein to the identity of its N‐
terminal residue. Degradation signals (degrons) that are targeted by the N‐end rule pathway …

Mitochondria are highly dynamic and undergo constant fusion and fission that are essential
for maintaining physiological functions of cells. Although dysfunction of mitochondria has …

A method of treating a patient who has non-small cell lung carcinoma (NSCLC), lung cancer,
gastric cancer, and/or glioblastoma includes administering to said patient a composition …

Introduction Various multigene predictors of breast cancer clinical outcome have been
commercialized, but proved to be prognostic only for hormone receptor (HR) subsets …

Graphene and its derivatives have become important nanomaterials worldwide and have
potential medical applications including in vivo diagnosis, drug delivery, and photothermal …

The present invention relates to peptides, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …

Molecular chaperones were originally discovered as heat shock-induced proteins that
facilitate proper folding of proteins with non-native conformations. While the function of …

Copy-number variations (CNVs) are ubiquitous in cancer and often act as driver events, but
the effects of CNVs on the proteome of tumors are poorly understood. Here, we analyze …

miR-31 (microRNA-31) is frequently altered in numerous cancers. The aim of the present
study was to investigate the role of miR-31 in ESCC (oesophageal squamous cell …