Capillary electrophoresis is a powerful technique for the analysis of polar chiral compounds
and has been widely accepted for analytical enantioseparations of drug compounds in …

Botanicals are widely used and marketed as food supplements or cosmetics with particular
benefits for human health. Botanicals are products manufactured using natural components …

The “purity” of an organic compound typically refers, in practice, to an assignment of the
mass fraction content of the primary organic component present in the material. The “purity” …

对药品杂质谱的控制是保证药品安全有效的重要措施, 也是提升国产药品质量的关键环节.
自2010 年提出实施杂质谱控制的基本策略以来, 经近十年持续的努力, 国内已经形成了一个比较 …

Aim: Hollow-fiber-based supported liquid membrane was modified utilizing nanostructures
such as graphite, graphene oxide or nitrogen-doped graphene oxide, for electro-membrane …

In this paper, a novel approach for the efficient microextraction and determination of
anticancer drug, sunitinib from human samples is described. We synthesized a new …

Pharmaceutical development is mostly focused on the research leading to approval of a new
and viable active substance. However, there is a number of old generation compounds that …

A stressed degradation (oxidation) was employed to produce metabolites from an active
pharmaceutical ingredient (API) with large molecular weight (about 900 g/mol). An analytical …

Macitentan is a dual endothelin receptor antagonist indicated for the treatment of pulmonary
arterial hypertension, a chronic and complex disease. Under different stress conditions, such …

Rivaroxaban is an anticoagulant that presents as a mechanism of action the direct and
selective inhibition of activated coagulation factor X (FXa). This molecule has a chiral center …