Adenovirus E1B-55K controls SUMO-dependent degradation of antiviral cellular restriction factors
The human adenovirus species C type 5 (HAdV-C5) early region 1B 55 kDa (E1B-55K)
protein is a multifunctional protein that promotes viral replication and adenovirus-mediated …
protein is a multifunctional protein that promotes viral replication and adenovirus-mediated …
The Cajal body protein p80-coilin forms a complex with the adenovirus L4-22K protein and facilitates the nuclear export of adenovirus mRNA
Cajal bodies (CBs) are major sub-nuclear structures in most eucaryotic cells. In human
adenovirus 5 (Ad5) infection, CBs are reorganized into microfoci in the late phase of …
adenovirus 5 (Ad5) infection, CBs are reorganized into microfoci in the late phase of …
Inhibition of human adenovirus replication by TRIM35-mediated degradation of E1A
N Sun, J Zhang, C Zhang, T Xie, Z Zhang… - Journal of …, 2023 - Am Soc Microbiol
Human adenovirus (HAdV) is ubiquitous in the human population, constituting a significant
burden of global respiratory diseases. Children and individuals with low immunity are at risk …
burden of global respiratory diseases. Children and individuals with low immunity are at risk …
E1B-55K is a phosphorylation-dependent transcriptional and posttranscriptional regulator of viral gene expression in human adenovirus C5 infection
The multifunctional adenoviral E1B-55K phosphoprotein is a major regulator of viral
replication and plays key roles in virus-mediated cell transformation. While much is known …
replication and plays key roles in virus-mediated cell transformation. While much is known …
Adenovirus remodeling of the host proteome and host factors associated with viral genomes
Viral infections are associated with extensive remodeling of the cellular proteome. Viruses
encode gene products that manipulate host proteins to redirect cellular processes or subvert …
encode gene products that manipulate host proteins to redirect cellular processes or subvert …
The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53
L Göttig, S Jummer, L Staehler, P Groitl… - Journal of …, 2024 - Am Soc Microbiol
Human adenoviruses (HAdV) are classified as DNA tumor viruses due to their potential to
mediate oncogenic transformation in non-permissive mammalian cells and certain human …
mediate oncogenic transformation in non-permissive mammalian cells and certain human …
Role of mouse adenovirus type 1 E4orf6-induced degradation of protein kinase R in pathogenesis
DF Edwards, III, EA Pereira, LA Castro-Jorge… - Journal of …, 2024 - journals.asm.org
Protein kinase R (PKR) is an interferon-induced antiviral protein activated by
autophosphorylation in response to double strand DNA (dsRNA) and other stimuli. Activated …
autophosphorylation in response to double strand DNA (dsRNA) and other stimuli. Activated …
Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism
Z Hajikhezri, Y Kaira, E Schubert, M Darweesh… - Journal of …, 2023 - Am Soc Microbiol
Human adenoviruses (HAdVs) are widespread pathogens causing a variety of diseases. A
well-controlled expression of virus capsid mRNAs originating from the major late …
well-controlled expression of virus capsid mRNAs originating from the major late …
Nuclear ribonucleoprotein RALY downregulates foot-and-mouth disease virus replication but antagonized by viral 3C protease
J Wu, C Sun, J Guan, SW Abdullah, X Wang… - Microbiology …, 2024 - Am Soc Microbiol
The internal ribosome entry site (IRES) element constitutes a cis-acting RNA regulatory
sequence that recruits the ribosomal initiation complex in a cap-independent manner …
sequence that recruits the ribosomal initiation complex in a cap-independent manner …
Mouse Adenovirus Type 1 E4orf6 Induces PKR Degradation
B Tejera-Hernández, DE Goodman… - Journal of …, 2022 - Am Soc Microbiol
Protein kinase R (PKR) is a cellular kinase involved in the antiviral response. The
inactivation or inhibition of this protein is a conserved activity in DNA and RNA virus …
inactivation or inhibition of this protein is a conserved activity in DNA and RNA virus …