[HTML][HTML] Cytokines and CNS development
BE Deverman, PH Patterson - Neuron, 2009 - cell.com
Cytokines are pleotrophic proteins that coordinate the host response to infection as well as
mediate normal, ongoing signaling between cells of nonimmune tissues, including the …
mediate normal, ongoing signaling between cells of nonimmune tissues, including the …
Reactive astrocytes and therapeutic potential in focal ischemic stroke
GR Choudhury, S Ding - Neurobiology of disease, 2016 - Elsevier
Astrocytes are specialized and the most abundant cell type in the central nervous system
(CNS). They play important roles in the physiology of the brain. Astrocytes are also critically …
(CNS). They play important roles in the physiology of the brain. Astrocytes are also critically …
[HTML][HTML] Timing is everything: making neurons versus glia in the developing cortex
FD Miller, AS Gauthier - Neuron, 2007 - cell.com
During development of the mammalian nervous system, neural stem cells generate neurons
first and glia second, thereby allowing the initial establishment of neural circuitry, and …
first and glia second, thereby allowing the initial establishment of neural circuitry, and …
[HTML][HTML] Notch in the vertebrate nervous system: an old dog with new tricks
T Pierfelice, L Alberi, N Gaiano - Neuron, 2011 - cell.com
The Notch pathway is prominent among those known to regulate neural development in
vertebrates. Notch receptor activation can inhibit neurogenesis, maintain neural progenitor …
vertebrates. Notch receptor activation can inhibit neurogenesis, maintain neural progenitor …
Cellular and molecular introduction to brain development
X Jiang, J Nardelli - Neurobiology of disease, 2016 - Elsevier
Advances in the study of brain development over the last decades, especially recent findings
regarding the evolutionary expansion of the human neocortex, and large-scale analyses of …
regarding the evolutionary expansion of the human neocortex, and large-scale analyses of …
[HTML][HTML] Basic helix-loop-helix factors in cortical development
SE Ross, ME Greenberg, CD Stiles - Neuron, 2003 - cell.com
Transcription factors with bHLH motifs modulate critical events in the development of the
mammalian neocortex. Multipotent cortical progenitors are maintained in a proliferative state …
mammalian neocortex. Multipotent cortical progenitors are maintained in a proliferative state …
Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling
Although the Notch and JAK–STAT signalling pathways fulfill overlapping roles in growth
and differentiation regulation, no coordination mechanism has been proposed to explain …
and differentiation regulation, no coordination mechanism has been proposed to explain …
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
DNA methylation is a major epigenetic factor that has been postulated to regulate cell
lineage differentiation. We report here that conditional gene deletion of the maintenance …
lineage differentiation. We report here that conditional gene deletion of the maintenance …
A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis
F He, W Ge, K Martinowich, S Becker-Catania… - Nature …, 2005 - nature.com
During development of the CNS, neurons and glia are generated in a sequential manner.
The mechanism underlying the later onset of gliogenesis is poorly understood, although the …
The mechanism underlying the later onset of gliogenesis is poorly understood, although the …
Molecular control of neurogenesis: a view from the mammalian cerebral cortex
B Martynoga, D Drechsel… - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The mammalian nervous system is the most complex organ of any living organism. How this
complexity is generated during neural development is just beginning to be elucidated. This …
complexity is generated during neural development is just beginning to be elucidated. This …