Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

JG Beeson, DR Drew, MJ Boyle, G Feng… - FEMS microbiology …, 2016 - academic.oup.com
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

Advances and challenges in malaria vaccine development

PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Malaria caused by Plasmodium falciparum remains a major public health threat, especially
among children and pregnant women in Africa. An effective malaria vaccine would be a …

A review of malaria vaccine clinical projects based on the WHO rainbow table

L Schwartz, GV Brown, B Genton, VS Moorthy - Malaria journal, 2012 - Springer
Abstract Development and Phase 3 testing of the most advanced malaria vaccine, RTS,
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

JG Beeson, L Kurtovic, C Dobaño, DH Opi… - Science translational …, 2019 - science.org
Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …

[HTML][HTML] Recent advances in recombinant protein-based malaria vaccines

SJ Draper, E Angov, T Horii, LH Miller, P Srinivasan… - Vaccine, 2015 - Elsevier
Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …

Host-parasite interactions during Plasmodium infection: Implications for immunotherapies

P Chandley, R Ranjan, S Kumar, S Rohatgi - Frontiers in Immunology, 2023 - frontiersin.org
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Protection against malaria by MSP3 candidate vaccine

SB Sirima, S Cousens, P Druilhe - New England Journal of …, 2011 - Mass Medical Soc
Protection against Malaria by MSP3 Candidate Vaccine | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36

NMQ Palacpac, E Ntege, A Yeka, B Balikagala… - PLoS …, 2013 - journals.plos.org
Background Up to now a malaria vaccine remains elusive. The Plasmodium falciparum
serine repeat antigen-5 formulated with aluminum hydroxyl gel (BK-SE36) is a blood-stage …

Peptide-based vaccines

RJ Nevagi, I Toth, M Skwarczynski - Peptide applications in biomedicine …, 2018 - Elsevier
Vaccination is a cost-effective approach to prevent, treat, and eradicate infectious diseases
and cancer. Classical whole-organism vaccines may have several pitfalls such as the …

Blood-stage malaria vaccines—recent progress and future challenges

AL Goodman, SJ Draper - Annals of Tropical Medicine & …, 2010 - Taylor & Francis
Plasmodium falciparum malaria is a major global health problem, responsible for up to 1
million deaths each year. Major efforts have been made to develop an effective vaccine …