Fifty Years of Research in ARDS. Spontaneous Breathing during Mechanical Ventilation. Risks, Mechanisms, and Management
T Yoshida, Y Fujino, MBP Amato… - American journal of …, 2017 - atsjournals.org
Spontaneous respiratory effort during mechanical ventilation has long been recognized to
improve oxygenation, and because oxygenation is a key management target, such effort …
improve oxygenation, and because oxygenation is a key management target, such effort …
[HTML][HTML] Noninvasive respiratory support and patient self-inflicted lung injury in COVID-19: a narrative review
COVID-19 pneumonia is associated with hypoxaemic respiratory failure, ranging from mild
to severe. Because of the worldwide shortage of ICU beds, a relatively high number of …
to severe. Because of the worldwide shortage of ICU beds, a relatively high number of …
Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome
Purpose Experimental animal models of acute respiratory distress syndrome (ARDS) have
shown that the updated airway pressure release ventilation (APRV) methodologies may …
shown that the updated airway pressure release ventilation (APRV) methodologies may …
Spontaneously regulated vs. controlled ventilation of acute lung injury/acute respiratory distress syndrome
JJ Marini - Current opinion in critical care, 2011 - journals.lww.com
Optimizing gas exchange, avoiding lung injury, and preserving respiratory muscle strength
and endurance are vital therapeutic objectives for managing acute lung injury. Accordingly …
and endurance are vital therapeutic objectives for managing acute lung injury. Accordingly …
Fifty Years of Research in ARDS.Gas Exchange in Acute Respiratory Distress Syndrome
P Radermacher, SM Maggiore… - American journal of …, 2017 - atsjournals.org
Acute respiratory distress syndrome (ARDS) is characterized by severe impairment of gas
exchange. Hypoxemia is mainly due to intrapulmonary shunt, whereas increased alveolar …
exchange. Hypoxemia is mainly due to intrapulmonary shunt, whereas increased alveolar …
Physiologic effects of noninvasive ventilation
NR MacIntyre - Respiratory care, 2019 - rc.rcjournal.com
Noninvasive ventilation (NIV) has a number of physiologic effects similar to invasive
ventilation. The major effects are to augment minute ventilation and reduce muscle loading …
ventilation. The major effects are to augment minute ventilation and reduce muscle loading …
Volume-controlled ventilation does not prevent injurious inflation during spontaneous effort
T Yoshida, S Nakahashi, MAM Nakamura… - American journal of …, 2017 - atsjournals.org
Rationale: Spontaneous breathing during mechanical ventilation increases transpulmonary
pressure and Vt, and worsens lung injury. Intuitively, controlling Vt and transpulmonary …
pressure and Vt, and worsens lung injury. Intuitively, controlling Vt and transpulmonary …
High failure rate of noninvasive oxygenation strategies in critically ill subjects with acute hypoxemic respiratory failure due to COVID-19
LS Menga, L Delle Cese, F Bongiovanni… - Respiratory …, 2021 - rc.rcjournal.com
BACKGROUND: The efficacy of noninvasive oxygenation strategies (NIOS) in treating
COVID-19 disease is unknown. We conducted a prospective observational study to assess …
COVID-19 disease is unknown. We conducted a prospective observational study to assess …
Impact of spontaneous breathing during mechanical ventilation in acute respiratory distress syndrome
T Yoshida, MBP Amato, BP Kavanagh… - Current opinion in …, 2019 - journals.lww.com
We update and summarize the role of spontaneous breathing during mechanical ventilation
in ARDS, which can be beneficial or deleterious, depending on the strength of spontaneous …
in ARDS, which can be beneficial or deleterious, depending on the strength of spontaneous …
Precision medicine and heterogeneity of treatment effect in therapies for ARDS
YA Khan, E Fan, ND Ferguson - Chest, 2021 - Elsevier
ARDS is a clinically heterogeneous syndrome, rather than a distinct disease. This
heterogeneity at least partially explains the difficulty in studying treatments for these patients …
heterogeneity at least partially explains the difficulty in studying treatments for these patients …