Dupilumab-induced hypereosinophilia: review of the literature and algorithm proposal for clinical management
M Caminati, B Olivieri, A Dama… - Expert Review of …, 2022 - Taylor & Francis
Introduction Dupilumab is a human monoclonal antibody that targets both IL-4 and IL-13
signaling. It is currently indicated for the treatment of asthma, moderate-to-severe atopic …
signaling. It is currently indicated for the treatment of asthma, moderate-to-severe atopic …
[HTML][HTML] The multidisciplinary approach to eosinophilia
GN Thomsen, MN Christoffersen… - Frontiers in …, 2023 - frontiersin.org
Eosinophilic granulocytes are normally present in low numbers in the bloodstream. Patients
with an increased number of eosinophilic granulocytes in the differential count (eosinophilia) …
with an increased number of eosinophilic granulocytes in the differential count (eosinophilia) …
Hypereosinophilia management in patients with type 2 chronic rhinosinusitis treated with dupilumab: preliminary results
A Vinciguerra, A Rampi, MR Yacoub, M Tresoldi… - European Archives of …, 2022 - Springer
Purpose Biological therapies are gaining relevance in the management of CRSwNP with
few adverse events reported. Among these, dupilumab, an anti-IL4-Ra monoclonal antibody …
few adverse events reported. Among these, dupilumab, an anti-IL4-Ra monoclonal antibody …
[HTML][HTML] Time-dependent blood eosinophilia count increases the risk of kidney allograft rejection
Background Growing evidence suggest that type 2 immune effectors play a role in solid
organ transplantation. The aim of this study was to evaluate the impact of blood count …
organ transplantation. The aim of this study was to evaluate the impact of blood count …
Temporal trends of blood eosinophilia in severe uncontrolled CRSwNP treated with dupilumab: a real-life study
E De Corso, C Montuori, S Baroni… - European Archives of …, 2024 - Springer
Purpose Induced eosinophilia is commonly related to dupilumab treatment. We analysed the
temporal trends of blood eosinophilia in patients with severe uncontrolled CRSwNP during …
temporal trends of blood eosinophilia in patients with severe uncontrolled CRSwNP during …
Eosinophilic airway diseases: basic science, clinical manifestations and future challenges
C Janson, L Bjermer, L Lehtimäki… - European Clinical …, 2022 - Taylor & Francis
Eosinophils have a broad range of functions, both homeostatic and pathological, mediated
through an array of cell surface receptors and specific secretory granules that promote …
through an array of cell surface receptors and specific secretory granules that promote …
[HTML][HTML] The role of peripheral eosinophilia in diagnosing lung disorders: experience from a single pneumonological center
J Fijolek, E Wiatr, D Piotrowska-Kownacka… - Multidisciplinary …, 2021 - ncbi.nlm.nih.gov
Background Eosinophilia is rare but one of the important reasons to refer patients to
pneumonological centers. Determining etiology of eosinophilia has practical implications for …
pneumonological centers. Determining etiology of eosinophilia has practical implications for …
Blood eosinophils: In quest of a Holy Grail for personalized asthma treatment with biologicals
M Jesenak, Z Diamant - Allergy, 2020 - Wiley Online Library
Treatment strategies for asthma are changing dramatically with many novel molecules
entering the market, especially within the group of biologicals. Intensive investigations …
entering the market, especially within the group of biologicals. Intensive investigations …
A retrospective cohort study of patients with eosinophilia referred to a tertiary centre
M Hougaard, GN Thomsen… - Danish Medical …, 2022 - portal.findresearcher.sdu.dk
Introduction. Patients with eosinophilia (an increased number of eosinophilic granulocytes>
0.5× 10 9/l in the blood) are encountered in all medical specialties and frequently need …
0.5× 10 9/l in the blood) are encountered in all medical specialties and frequently need …
[HTML][HTML] All-cause mortality and related factors in patients with varying degrees of peripheral blood eosinophilia
D Yilmaz, E Sahin - Medicine, 2024 - journals.lww.com
The aim of this study was to investigate all-cause mortality rates and related factors in
patients with different levels of eosinophilia. This retrospective cohort study was conducted …
patients with different levels of eosinophilia. This retrospective cohort study was conducted …