Introduction Dupilumab is a human monoclonal antibody that targets both IL-4 and IL-13
signaling. It is currently indicated for the treatment of asthma, moderate-to-severe atopic …

Eosinophilic granulocytes are normally present in low numbers in the bloodstream. Patients
with an increased number of eosinophilic granulocytes in the differential count (eosinophilia) …

Purpose Biological therapies are gaining relevance in the management of CRSwNP with
few adverse events reported. Among these, dupilumab, an anti-IL4-Ra monoclonal antibody …

Background Growing evidence suggest that type 2 immune effectors play a role in solid
organ transplantation. The aim of this study was to evaluate the impact of blood count …

Purpose Induced eosinophilia is commonly related to dupilumab treatment. We analysed the
temporal trends of blood eosinophilia in patients with severe uncontrolled CRSwNP during …

Eosinophils have a broad range of functions, both homeostatic and pathological, mediated
through an array of cell surface receptors and specific secretory granules that promote …

Background Eosinophilia is rare but one of the important reasons to refer patients to
pneumonological centers. Determining etiology of eosinophilia has practical implications for …

Treatment strategies for asthma are changing dramatically with many novel molecules
entering the market, especially within the group of biologicals. Intensive investigations …

Introduction. Patients with eosinophilia (an increased number of eosinophilic granulocytes>
0.5× 10 9/l in the blood) are encountered in all medical specialties and frequently need …

The aim of this study was to investigate all-cause mortality rates and related factors in
patients with different levels of eosinophilia. This retrospective cohort study was conducted …