The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Enteric glial biology, intercellular signalling and roles in gastrointestinal disease
L Seguella, BD Gulbransen - Nature reviews Gastroenterology & …, 2021 - nature.com
One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …
many functions normally attributed to enteric neurons involve interactions with enteric glial …
[HTML][HTML] Schwann cell functions in peripheral nerve development and repair
M Bosch-Queralt, R Fledrich, RM Stassart - Neurobiology of disease, 2023 - Elsevier
The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …
the most multifaceted cells of the body. During development, SCs secure neuronal survival …
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
Probiotics, prebiotics and epithelial tight junctions: a promising approach to modulate intestinal barrier function
Disruptions in the intestinal epithelial barrier can result in devastating consequences and a
multitude of disease syndromes, particularly among preterm neonates. The association …
multitude of disease syndromes, particularly among preterm neonates. The association …
Relationship between the gut microbiome and brain function
MH Mohajeri, G La Fata, RE Steinert… - Nutrition …, 2018 - academic.oup.com
It has become increasingly evident in recent years that the gut microbiome and the brain
communicate in a bidirectional manner, with each possibly affecting the other's functions …
communicate in a bidirectional manner, with each possibly affecting the other's functions …
Functional dyspepsia
P Enck, F Azpiroz, G Boeckxstaens… - Nature Reviews …, 2017 - nature.com
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders.
Functional dyspepsia comprises three subtypes with presumed different pathophysiology …
Functional dyspepsia comprises three subtypes with presumed different pathophysiology …
[HTML][HTML] Enteric glial cell heterogeneity regulates intestinal stem cell niches
MB Baghdadi, A Ayyaz, S Coquenlorge, B Chu… - Cell stem cell, 2022 - cell.com
The high turnover and regenerative capacity of the adult intestine relies on resident stem
cells located at the bottom of the crypt. The enteric nervous system consists of an abundant …
cells located at the bottom of the crypt. The enteric nervous system consists of an abundant …
[HTML][HTML] Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's …
Recent evidence provides support for involvement of the microbiota-gut-brain axis in
Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal …
Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal …
Aging microbiota-gut-brain axis in stroke risk and outcome
P Honarpisheh, RM Bryan, LD McCullough - Circulation research, 2022 - Am Heart Assoc
The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …
microbes and their host. Many environmental and host-related factors affect the gut …