Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

Testicular germ cells, which appear after the establishment of central tolerance, express
novel cell surface and intracellular proteins that can be recognized as 'foreign antigens' by …

Context Young boys treated with high-dose chemotherapy are often confronted with infertility
once they reach adulthood. Cryopreserving testicular tissue before chemotherapy and …

Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …

Starting from the period of testis differentiation, the Sertoli cell plays a pivotal role in the
development of a functional testis. FSH is the major mitotic factor for Sertoli cells. Because …

Sheep and goats are valuable livestock species that have been raised for their production of
meat, milk, fiber, and other by-products. Due to their suitable size, short gestation period …

Transplantation of spermatogonial stem cells into syngeneic or immunosuppressed recipient
mice or rats can result in donor-derived spermatogenesis and fertility. Recently, this …

Ectopic grafting of testicular tissue is a promising new approach that can be used to
preserve testicular function. This technique has been used recently to differentiate the …

Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

Identification and isolation of spermatogonial stem cells (SSCs) are a prerequisite for
culture, genetic manipulation, and/or transplantation research. In this study, we established …