Neuraxial patterning is a continuous process that extends over a protracted period of
development. During gastrulation a crude anteroposterior pattern, detectable by molecular …

In conclusion, it is obvious that many of the abnormalities in pattern formation and organ
formation that result from the exogenous addition of RA during embryogenesis are related at …

The broad spectrum herbicide glyphosate is widely used in agriculture worldwide. There has
been ongoing controversy regarding the possible adverse effects of glyphosate on the …

A number of studies have suggested that the active derivative of vitamin A, retinoic acid
(RA), may be important for early development of mammalian embryos 1, 2. Severe vitamin A …

Retinoic acid (RA), a derivative of vitamin A, plays a pivotal role in vertebrate development.
The level of RA may be determined by the balance between its synthesis and degradation …

Retinoic acid (RA) is a physiological agent that has a wide range of biological activity and
appears to regulate developmental programs of vertebrates. However, little is known about …

Retinoids are essential for normal development and both deficiency and excess of retinoic
acid (RA) are teratogenic. Retinoic acid response elements (RAREs) have been identified in …

We have identified from mouse the first mammalian β-carotene 15, 15′-dioxygenase (β-
CD), a crucial enzyme in development and metabolism that governs the de novo entry of …

Background: Retinoic acid (RA) is a morphogenetically active signalling molecule thought to
be involved in the development of several embryonic systems (based on its effect when …

Retinoic acid, a developmental signal implicated in the formation of the neural axis, is
present at high levels in the early embryonic trunk region, where it is synthesized by a novel …