[HTML][HTML] Three-component synthesis of C2F5-substituted pyrazoles from C2F5CH2NH2· HCl, NaNO2 and electron-deficient alkynes
PK Mykhailiuk - Beilstein Journal of Organic Chemistry, 2015 - beilstein-journals.org
A one-pot reaction between C 2 F 5 CH 2 NH 2· HCl, NaNO 2 and electron-deficient alkynes
gives C 2 F 5-substituted pyrazoles in excellent yields. The transformation smoothly …
gives C 2 F 5-substituted pyrazoles in excellent yields. The transformation smoothly …
Indazoles: Synthesis and Bond-Forming Heterocyclization
Indazoles (azaindoles) are heterocyclic compounds structurally related to indoles and can
be viewed as indole isosteres. The indazole moiety is a 10-π electron aromatic heterocyclic …
be viewed as indole isosteres. The indazole moiety is a 10-π electron aromatic heterocyclic …
Regioselective Synthesis of Polyfluoroalkyl Substituted 6, 7‐Dihydrobenzisoxazolones
Regioselective methods for synthesis of hitherto unreported both 6, 7‐dihydro‐1, 2‐
benzisoxazol‐4 (5H)‐ones and 6, 7‐dihydro‐2, 1‐benzisoxazol‐4 (5H)‐ones with …
benzisoxazol‐4 (5H)‐ones and 6, 7‐dihydro‐2, 1‐benzisoxazol‐4 (5H)‐ones with …
One-Pot Synthesis of Trifluoromethyl-Substituted Imidazobenz[1,2-d]- and -[1,2-c]isoxazoles
Abstract Synthesis of regioisomeric 8-trifluoromethyl-4, 5-dihydro-3 H-imidazo [4', 5': 5, 6]
benz [1, 2-d] isoxazoles and 8-trifluoromethyl-4, 5-dihydro-3 H-imidazo [4', 5': 3, 4] benz [1, 2 …
benz [1, 2-d] isoxazoles and 8-trifluoromethyl-4, 5-dihydro-3 H-imidazo [4', 5': 3, 4] benz [1, 2 …
Cytotoxic activity of perfluoroalkyl-substituted imidazoindazoles and imidazobenzisoxazoles
TS Khlebnikova, OV Panibrat, YA Piven… - Pharmaceutical …, 2021 - Springer
The cytotoxic activity of perfluoroalkyl imidazoindazoles and imidazobenzisoxazoles with
respect to MCF-7 (human breast carcinoma) and HepG2 cell lines (human hepatocellular …
respect to MCF-7 (human breast carcinoma) and HepG2 cell lines (human hepatocellular …
Однореакторный синтез трифторметилзамещенных имидазобенз[1,2-d]- и [1,2-c]изоксазолов
ТС Хлебникова, ЮА Пивень, ВГ Исакова… - Журнал общей …, 2020 - elibrary.ru
Осуществлен синтез региоизомерных 8-трифторметил-4, 5-дигидро-3Н-имидазо [4', 5':
5, 6] бенз [1, 2-d] изоксазолов и 8-трифторметил-4, 5-дигидро-3Н-имидазо [4', 5': 3, 4] …
5, 6] бенз [1, 2-d] изоксазолов и 8-трифторметил-4, 5-дигидро-3Н-имидазо [4', 5': 3, 4] …
Synthesis and transformations of perfluoroalkyl-containing 6,7-dihydro-1H-indazol-4(5H)-ones oximes
Abstract Refluxing 3-perfluoroalkyl-6, 7-dihydro-1 H-indazol-4 (5 H)-ones with 4-fold excess
of hydroxylamine hydrochloride in pyridine afforded their (E)-oximes. The obtained oximes …
of hydroxylamine hydrochloride in pyridine afforded their (E)-oximes. The obtained oximes …
Цитотоксическая активность перфторалкилзамещенных имидазоиндазолов и имидазобензизоксазолов
ТС Хлебникова, ОВ Панибрат, ЮА Пивень… - Химико …, 2021 - chem.folium.ru
Аннотация Исследована цитотоксическая активность перфторалкилзамещенных
имидазоиндазолов и имидазобензизоксазолов в отношении клеточных линий HepG2 …
имидазоиндазолов и имидазобензизоксазолов в отношении клеточных линий HepG2 …