Next-generation DNA sequencing methods
ER Mardis - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Recent scientific discoveries that resulted from the application of next-generation DNA
sequencing technologies highlight the striking impact of these massively parallel platforms …
sequencing technologies highlight the striking impact of these massively parallel platforms …
Back to the future: museum specimens in population genetics
P Wandeler, PEA Hoeck, LF Keller - Trends in ecology & evolution, 2007 - cell.com
Museums and other natural history collections (NHC) worldwide house millions of
specimens. With the advent of molecular genetic approaches these collections have …
specimens. With the advent of molecular genetic approaches these collections have …
Late Quaternary dynamics of Arctic biota from ancient environmental genomics
During the last glacial–interglacial cycle, Arctic biotas experienced substantial climatic
changes, yet the nature, extent and rate of their responses are not fully understood …
changes, yet the nature, extent and rate of their responses are not fully understood …
A draft sequence of the Neandertal genome
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …
Europe and western Asia before disappearing 30,000 years ago. We present a draft …
[HTML][HTML] Complete genomes reveal signatures of demographic and genetic declines in the woolly mammoth
The processes leading up to species extinctions are typically characterized by prolonged
declines in population size and geographic distribution, followed by a phase in which …
declines in population size and geographic distribution, followed by a phase in which …
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
ABSTRACT DNA sequences determined from ancient organisms have high error rates,
primarily due to uracil bases created by cytosine deamination. We use synthetic …
primarily due to uracil bases created by cytosine deamination. We use synthetic …
The derived FOXP2 variant of modern humans was shared with Neandertals
Although many animals communicate vocally, no extant creature rivals modern humans in
language ability. Therefore, knowing when and under what evolutionary pressures our …
language ability. Therefore, knowing when and under what evolutionary pressures our …
[HTML][HTML] A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing
A complete mitochondrial (mt) genome sequence was reconstructed from a 38,000 year-old
Neandertal individual with 8341 mtDNA sequences identified among 4.8 Gb of DNA …
Neandertal individual with 8341 mtDNA sequences identified among 4.8 Gb of DNA …
Analysis of one million base pairs of Neanderthal DNA
Neanderthals are the extinct hominid group most closely related to contemporary humans,
so their genome offers a unique opportunity to identify genetic changes specific to …
so their genome offers a unique opportunity to identify genetic changes specific to …
Pleistocene rewilding: an optimistic agenda for twenty-first century conservation
C Josh Donlan, J Berger, CE Bock… - The American …, 2006 - journals.uchicago.edu
Large vertebrates are strong interactors in food webs, yet they were lost from most
ecosystems after the dispersal of modern humans from Africa and Eurasia. We call for …
ecosystems after the dispersal of modern humans from Africa and Eurasia. We call for …