Effects of diabetes on hippocampal neurogenesis: links to cognition and depression

N Ho, MS Sommers, I Lucki - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Diabetes often leads to a number of complications involving brain function, including
cognitive decline and depression. In addition, depression is a risk factor for developing …

Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease

V Frisardi, V Solfrizzi, D Seripa, C Capurso… - Ageing research …, 2010 - Elsevier
A growing body of epidemiological evidence suggested that metabolic syndrome (MetS) and
Mets components (impaired glucose tolerance, abdominal or central obesity, hypertension …

Inside the diabetic brain: role of different players involved in cognitive decline

JM Gaspar, FI Baptista, MP Macedo… - ACS chemical …, 2016 - ACS Publications
Diabetes mellitus is the most common metabolic disease, and its prevalence is increasing. A
growing body of evidence, both in animal models and epidemiological studies, has …

Cerebrovascular complications of diabetes: focus on stroke

A Ergul, A Kelly-Cobbs, M Abdalla… - … , Metabolic & Immune …, 2012 - ingentaconnect.com
Cerebrovascular complications make diabetic patients 2-6 times more susceptible to a
stroke event and this risk is magnified in younger individuals and in patients with …

[HTML][HTML] Inflammation and insulin resistance as risk factors and potential therapeutic targets for Alzheimer's disease

A Vinuesa, C Pomilio, A Gregosa… - Frontiers in …, 2021 - frontiersin.org
Overnutrition and modern diets containing high proportions of saturated fat are among the
major factors contributing to a low-grade state of inflammation, hyperglycemia and …

Potential benefits of mindfulness-based interventions in mild cognitive impairment and Alzheimer's disease: an interdisciplinary perspective

E Larouche, C Hudon, S Goulet - Behavioural brain research, 2015 - Elsevier
The present article is based on the premise that the risk of developing Alzheimer's disease
(AD) from its prodromal phase (mild cognitive impairment; MCI) is higher when adverse …

Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia

Y Li, Y Zhang, L Wang, P Wang, Y Xue, X Li, X Qiao… - Autophagy, 2017 - Taylor & Francis
The majority of diabetic patients develop neuropathy and there is an increasing prevalence
of neurodegeneration in the central nervous system (CNS). However, the mechanism …

Early exposure to a high-fat diet impacts on hippocampal plasticity: implication of microglia-derived exosome-like extracellular vesicles

A Vinuesa, M Bentivegna, G Calfa, F Filipello… - Molecular …, 2019 - Springer
Adolescence is a transitional period from childhood to adulthood characterized by puberty
and brain maturation involving behavioral changes and environmental vulnerability. Diet is …

Models and mechanisms for hippocampal dysfunction in obesity and diabetes

AM Stranahan - Neuroscience, 2015 - Elsevier
Clinical studies suggest that obesity and Type 2 (insulin-resistant) diabetes impair the
structural integrity of medial temporal lobe regions involved in memory and confer greater …

[HTML][HTML] Short-term environmental enrichment enhances adult neurogenesis, vascular network and dendritic complexity in the hippocampus of type 1 diabetic mice

J Beauquis, P Roig, AF De Nicola, F Saravia - PloS one, 2010 - journals.plos.org
Background Several brain disturbances have been described in association to type 1
diabetes in humans. In animal models, hippocampal pathological changes were reported …