Evaluation of the use of therapeutic peptides for cancer treatment
Cancer along with cardiovascular disease are the main causes of death in the industrialised
countries around the World. Conventional cancer treatments are losing their therapeutic …
countries around the World. Conventional cancer treatments are losing their therapeutic …
Anticancer peptides mechanisms, simple and complex
P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …
has emerged as a new approach in treatment of diseases including cancer. Using anti …
FOXO factors and breast cancer: outfoxing endocrine resistance
M Bullock - Endocrine-related cancer, 2016 - erc.bioscientifica.com
Four cardiac hormones, namely atrial natriuretic peptide, vessel dilator, kaliuretic peptide,
and long-acting natriuretic peptide, reduce up to 97% of all cancer cells in vitro. These four …
and long-acting natriuretic peptide, reduce up to 97% of all cancer cells in vitro. These four …
ENaC is regulated by natriuretic peptide receptor-dependent cGMP signaling
LJ Guo, AA Alli, DC Eaton… - American Journal of …, 2013 - journals.physiology.org
Epithelial sodium channels (ENaCs) located at the apical membrane of polarized epithelial
cells are regulated by the second messenger guanosine 3′, 5′-cyclic monophosphate …
cells are regulated by the second messenger guanosine 3′, 5′-cyclic monophosphate …
CD74-AKT Axis Is a Potential Therapeutic Target in Triple-Negative Breast Cancer
Simple Summary Triple-negative breast cancer is a highly aggressive type of invasive breast
cancer in which the patients frequently develop resistance to inhibitors used for induction of …
cancer in which the patients frequently develop resistance to inhibitors used for induction of …
Peptides for diagnosis and treatment of colorectal cancer
S Shapira, A Fokra, N Arber… - Current medicinal …, 2014 - ingentaconnect.com
Colorectal cancer (CRC) is a major health concern worldwide, as it is the third most
frequently diagnosed cancer and the second leading cause of cancer-related death. There …
frequently diagnosed cancer and the second leading cause of cancer-related death. There …
Natriuretic peptides: Another tool for the management of cancer?
J Balaguer, J Garcia-Foncillas, J Tunon - Critical Reviews in Oncology …, 2024 - Elsevier
The connection between heart failure (HF) and cancer through multiple pathways such as
inflammation, oxidative stress, and neurohormonal activation, among others, is well …
inflammation, oxidative stress, and neurohormonal activation, among others, is well …
C Type Natriuretic Peptide Receptor Activation Inhibits Sodium Channel Activity in Human Aortic Endothelial Cells by Activating the Diacylglycerol-Protein Kinase C …
L Yu, MZ Nouri, LP Liu, N Bala, ND Denslow… - International Journal of …, 2022 - mdpi.com
The C-type natriuretic peptide receptor (NPRC) is expressed in many cell types and binds all
natriuretic peptides with high affinity. Ligand binding results in the activation or inhibition of …
natriuretic peptides with high affinity. Ligand binding results in the activation or inhibition of …
Cardiac and renal hormones: anticancer effects in vitro and in vivo
DL Vesely - Journal of Investigative Medicine, 2009 - journals.sagepub.com
Background Four cardiovascular hormones, ie, vessel dilator, long-acting natriuretic peptide,
kaliuretic peptide, and atrial natriuretic peptide each at 1 mmol/L, decrease up to 97% of …
kaliuretic peptide, and atrial natriuretic peptide each at 1 mmol/L, decrease up to 97% of …
Cardiac hormones target nuclear oncogenes c‐F os and c‐J un in carcinoma cells
NJ Manimala, CD Frost, ML Lane… - European Journal of …, 2013 - Wiley Online Library
Background c‐F os is a cellular proto‐oncogene which dimerizes with c‐J un proto‐
oncogene to form AP‐1 transcription factor, which upregulates transcription of genes …
oncogene to form AP‐1 transcription factor, which upregulates transcription of genes …