ABSTRACT TACC3 is the most oncogenic member of the transforming acidic coiled-coil
domain-containing protein (TACC) family. It is one of the major recruitment factors of distinct …

The FGFR signaling pathway is integral to cellular activities, including proliferation,
differentiation, and survival. Dysregulation of this pathway is implicated in numerous human …

Little is known about the prospective association between autosomal mosaic chromosomal
alterations (mCAs), a group of large-scale somatic mutations on autosomes, and bladder …

Tobacco smoking is the most important risk factor for bladder cancer. Previous studies have
identified the N‐acetyltransferase (NAT2) gene in association with bladder cancer risk. The …

Abstract FGFR3 and PIK3CA are among the most frequently mutated genes in bladder
tumors. We hypothesized that recurrent mutations in these genes might be caused by …

Background Bladder cancer (BLCA) research in Koreans is still lacking, especially in
focusing on the prediction of BLCA. The current study aimed to discover metabolic …

We performed a series of integrative analyses including transcriptome-wide association
studies (TWASs) and proteome-wide association studies (PWASs) of renal cell carcinoma …

Matrix metalloproteinase (MMP)-2 and-9, which degrade type IV collagen, are linked to
cancer invasion and metastasis. Gene polymorphisms in MMP-2 and MMP-9 can influence …

Genomic studies of inherited and acquired variation are changing the landscape of our
understanding of the causes of urologic cancers and providing important translational …

Tobacco carcinogens metabolism-related genes (TCMGs) could generate reactive
metabolites of tobacco carcinogens, which subsequently contributed to multiple diseases …