Morphogenesis is one of the most remarkable examples of biological pattern formation.
Despite substantial progress in the field, we still do not understand the organizational …

The Drosophila wing imaginal disc is a tissue of undifferentiated cells that are precursors of
the wing and most of the notum of the adult fly. The wing disc first forms during …

In the mid-1960s, bone morphogenetic proteins (BMPs) were first identified in the extracts of
bone to have the remarkable ability to induce heterotopic bone. When the Drosophila gene …

Orientational order, encoded in anisotropic fields, plays an important role during the
development of an organism. A striking example of this is the freshwater polyp Hydra, where …

How complex 3D tissue shape emerges during animal development remains an important
open question in biology and biophysics. Here, we discover a mechanism for 3D epithelial …

Biological cells can actively tune their intracellular architecture according to their overall
shape. Here we explore the rheological implication of such coupling in a minimal model of a …

The rheology of biological tissue is key to processes such as embryo development, wound
healing, and cancer metastasis. Vertex models of confluent tissue monolayers have …

During vertebrate gastrulation, an embryo transforms from a layer of epithelial cells into a
multilayered gastrula. This process requires the coordinated movements of hundreds to tens …

Large-scale tissue deformation which is fundamental to tissue development hinges on local
cellular rearrangements, such as T1 transitions. In the realm of the multi-phase field model …

In amorphous solids as in tissues, neighbor exchanges can relax local stresses and allow
the material to flow. In this paper, we use an anisotropic vertex model to study T1 …