Microtubules: From understanding their dynamics to using them as potential therapeutic targets
Y Ilan - Journal of cellular physiology, 2019 - Wiley Online Library
Microtubules (MT) and actin microfilaments are dynamic cytoskeleton components involved
in a range of intracellular processes. MTs play a role in cell division, beating of cilia and …
in a range of intracellular processes. MTs play a role in cell division, beating of cilia and …
[HTML][HTML] mRNA targeting, transport and local translation in eukaryotic cells: from the classical view to a diversity of new concepts
KA Lashkevich, SE Dmitriev - Molecular Biology, 2021 - Springer
Spatial organization of protein biosynthesis in the eukaryotic cell has been studied for more
than fifty years, thus many facts have already been included in textbooks. According to the …
than fifty years, thus many facts have already been included in textbooks. According to the …
Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation
L Coutinho de Oliveira, L Volpon… - Proceedings of the …, 2019 - National Acad Sciences
Viruses have transformed our understanding of mammalian RNA processing, including
facilitating the discovery of the methyl-7-guanosine (m7G) cap on the 5′ end of RNAs. The …
facilitating the discovery of the methyl-7-guanosine (m7G) cap on the 5′ end of RNAs. The …
Molecular basis of mRNA transport by a kinesin-1–atypical tropomyosin complex
L Dimitrova-Paternoga, PKA Jagtap… - Genes & …, 2021 - genesdev.cshlp.org
Kinesin-1 carries cargos including proteins, RNAs, vesicles, and pathogens over long
distances within cells. The mechanochemical cycle of kinesins is well described, but how …
distances within cells. The mechanochemical cycle of kinesins is well described, but how …
Stress granule and P-body clearance: Seeking coherence in acts of disappearance
JR Buchan - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Stress granules and P-bodies are conserved cytoplasmic biomolecular condensates whose
assembly and composition are well documented, but whose clearance mechanisms remain …
assembly and composition are well documented, but whose clearance mechanisms remain …
[HTML][HTML] Microtubule-driven stress granule dynamics regulate inhibitory immune checkpoint expression in T cells
DM Franchini, O Lanvin, M Tosolini, EP de Campaigno… - Cell Reports, 2019 - cell.com
Despite the clinical success of blocking inhibitory immune checkpoint receptors such as
programmed cell death-1 (PD-1) in cancer, the mechanisms controlling the expression of …
programmed cell death-1 (PD-1) in cancer, the mechanisms controlling the expression of …
Uncovering the role of cytoskeleton proteins in the formation of neutrophil extracellular traps
C Du, N Cai, J Dong, C Xu, Q Wang, Z Zhang… - International …, 2023 - Elsevier
Neutrophils are a type of lymphocyte involved in innate immune defense. In response to
specific stimuli, these phagocytic cells undergo a unique form of cell death, NETosis, during …
specific stimuli, these phagocytic cells undergo a unique form of cell death, NETosis, during …
Molecular dissection of defense response of pears induced by the biocontrol yeast, Wickerhamomyces anomalus using transcriptomics and proteomics approaches
Q Zhang, L Zhao, B Li, X Gu, X Zhang, NS Boateng… - Biological Control, 2020 - Elsevier
Wickerhamomyces anomalus, a yeast used for the biocontrol of postharvest diseases of
fruits, significantly reduces the natural decay of pear fruit without causing any adverse …
fruits, significantly reduces the natural decay of pear fruit without causing any adverse …
Regulation of aquaporin‐4 expression in the central nervous system investigated using M23‐AQP4 null mouse
In astrocytes, unknown mechanisms regulate the expression of M1 and M23 isoforms of
water channel aquaporin‐4 (M1‐AQP4 and M23‐AQP4). The ratio between these two …
water channel aquaporin‐4 (M1‐AQP4 and M23‐AQP4). The ratio between these two …
Nanostructure of Functional Larotaxel Liposomes Decorated with Guanine‐Rich Quadruplex Nucleotide–Lipid Derivative for Treatment of Resistant Breast Cancer
X Li, J Li, J Xu, K Chen, Z Zhang, J Duan, Q Luo, Y Du… - Small, 2021 - Wiley Online Library
Breast cancer is the most common malignant disease in women all over the world and its
chemotherapy outcome is restricted by multidrug resistance. Here, a nanostructure by …
chemotherapy outcome is restricted by multidrug resistance. Here, a nanostructure by …