Core commitments for field trials of gene drive organisms
Gene drive organisms (GDOs), whose genomes have been genetically engineered to
spread a desired allele through a population, have the potential to transform the way …
spread a desired allele through a population, have the potential to transform the way …
Suppressing mosquito populations with precision guided sterile males
The mosquito Aedes aegypti is the principal vector for arboviruses including dengue/yellow
fever, chikungunya, and Zika virus, infecting hundreds of millions of people annually …
fever, chikungunya, and Zika virus, infecting hundreds of millions of people annually …
2-Locus Cleave and Rescue selfish elements harness a recombination rate-dependent generational clock for self limiting gene drive
G Oberhofer, T Ivy, BA Hay - bioRxiv, 2020 - biorxiv.org
Self-limiting gene drive allows control over the spread and fate of linked traits. Cleave and
Rescue (ClvR) elements create self-sustaining drive and comprise a DNA sequence …
Rescue (ClvR) elements create self-sustaining drive and comprise a DNA sequence …
A comparative assessment of self-limiting genetic control strategies for population suppression
Y Han, J Champer - bioRxiv, 2024 - biorxiv.org
Genetic control strategies are promising solutions for control of pest populations and
invasive species. Methods utilizing repeated releases of males such as Sterile Insect …
invasive species. Methods utilizing repeated releases of males such as Sterile Insect …