Does functional MRI detect activation in white matter? A review of emerging evidence, issues, and future directions

JR Gawryluk, EL Mazerolle, RCN D'Arcy - Frontiers in neuroscience, 2014 - frontiersin.org
Functional magnetic resonance imaging (fMRI) is a non-invasive technique that allows for
visualization of activated brain regions. Until recently, fMRI studies have focused on gray …

The contribution of functional magnetic resonance imaging to the understanding of the effects of acute physical exercise on cognition

F Herold, N Aye, N Lehmann, M Taubert, NG Müller - Brain sciences, 2020 - mdpi.com
The fact that a single bout of acute physical exercise has a positive impact on cognition is
well-established in the literature, but the neural correlates that underlie these cognitive …

Characterization of the hemodynamic response function in white matter tracts for event-related fMRI

M Li, AT Newton, AW Anderson, Z Ding… - Nature …, 2019 - nature.com
Accurate estimates of the BOLD hemodynamic response function (HRF) are crucial for the
interpretation and analysis of event-related functional MRI data. To date, however, there …

Regional and network properties of white matter function in Parkinson's disease

GJ Ji, C Ren, Y Li, J Sun, T Liu, Y Gao… - Human Brain …, 2019 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder with dysfunction in cortices as
well as white matter (WM) tracts. While the changes to WM structure have been extensively …

Alterations in amplitude of low frequency fluctuation in treatment‐naïve major depressive disorder measured with resting‐state fMRI

J Liu, L Ren, FY Womer, J Wang, G Fan… - Human brain …, 2014 - Wiley Online Library
There are limited resting‐state functional magnetic resonance imaging (fMRI) studies in
major depressive disorder (MDD). Of these studies, functional connectivity analyses are …

[HTML][HTML] Increased myelination plays a central role in white matter neuroplasticity

ED Kirby, TO Frizzell, LA Grajauskas, X Song… - NeuroImage, 2022 - Elsevier
White matter (WM) neuroplasticity in the human brain has been tracked non-invasively using
advanced magnetic resonance imaging techniques, with increasing evidence for improved …

White matter fMRI activation cannot be treated as a nuisance regressor: Overcoming a historical blind spot

LA Grajauskas, T Frizzell, X Song… - Frontiers in …, 2019 - frontiersin.org
Despite past controversies, increasing evidence has led to acceptance that white matter
activity is detectable using functional magnetic resonance imaging (fMRI). In spite of this …

Whole-brain, gray, and white matter time-locked functional signal changes with simple tasks and model-free analysis

KG Schilling, M Li, F Rheault, Y Gao… - Proceedings of the …, 2023 - National Acad Sciences
Recent studies have revealed the production of time-locked blood oxygenation level–
dependent (BOLD) functional MRI (fMRI) signals throughout the entire brain in response to …

Imaging functional neuroplasticity in human white matter tracts

TO Frizzell, E Phull, M Khan, X Song… - Brain Structure and …, 2022 - Springer
Magnetic resonance imaging (MRI) studies are sensitive to biological mechanisms of
neuroplasticity in white matter (WM). In particular, diffusion tensor imaging (DTI) has been …

Contribution of systemic vascular effects to fMRI activity in white matter

PS Özbay, C Chang, D Picchioni, H Mandelkow… - Neuroimage, 2018 - Elsevier
To investigate a potential contribution of systemic physiology to recently reported BOLD fMRI
signals in white matter, we compared photo-plethysmography (PPG) and whole-brain fMRI …