Endocrine disrupting chemicals and disease susceptibility

TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Polystyrene nanoplastics toxicity to zebrafish: dysregulation of the brain–intestine–microbiota axis

M Teng, X Zhao, C Wang, C Wang, JC White, W Zhao… - ACS …, 2022 - ACS Publications
In animal species, the brain–gut axis is a complex bidirectional network between the
gastrointestinal (GI) tract and the central nervous system (CNS) consisting of numerous …

Toxicopathological effects of the sunscreen UV filter, oxybenzone (benzophenone-3), on coral planulae and cultured primary cells and its environmental …

CA Downs, E Kramarsky-Winter, R Segal… - Archives of …, 2016 - Springer
Abstract Benzophenone-3 (BP-3; oxybenzone) is an ingredient in sunscreen lotions and
personal-care products that protects against the damaging effects of ultraviolet light …

Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption

LN Vandenberg, MV Maffini, C Sonnenschein… - Endocrine …, 2009 - academic.oup.com
In 1991, a group of 21 scientists gathered at the Wingspread Conference Center to discuss
evidence of developmental alterations observed in wildlife populations after chemical …

Carotenoid-based signals in behavioural ecology: a review

Svensson, Wong - Behaviour, 2011 - brill.com
Carotenoids are among the most prevalent pigments used in animal signals and are also
important for a range of physiological functions. These concomitant roles have made …

An automated fitting procedure and software for dose-response curves with multiphasic features

GY Di Veroli, C Fornari, I Goldlust, G Mills, SB Koh… - Scientific reports, 2015 - nature.com
In cancer pharmacology (and many other areas), most dose-response curves are
satisfactorily described by a classical Hill equation (ie 4 parameters logistical). Nevertheless …

Bisphenol S disrupts estradiol-induced nongenomic signaling in a rat pituitary cell line: effects on cell functions

R Viñas, CS Watson - Environmental health perspectives, 2013 - ehp.niehs.nih.gov
Background: Bisphenol A (BPA) is a well-known endocrine disruptor that imperfectly mimics
the effects of physiologic estrogens via membrane-bound estrogen receptors (mERα, mERβ …

Elucidating the links between endocrine disruptors and neurodevelopment

TT Schug, AM Blawas, K Gray, JJ Heindel… - …, 2015 - academic.oup.com
Recent data indicate that approximately 12% of children in the United States are affected by
neurodevelopmental disorders, including attention deficit hyperactivity disorder, learning …

Multiple hormonal activities of UV filters and comparison of in vivo and in vitro estrogenic activity of ethyl-4-aminobenzoate in fish

PY Kunz, K Fent - Aquatic Toxicology, 2006 - Elsevier
UV filters have been detected in surface water, wastewater and fish, and some of them are
estrogenic in fish. At present, little is known about their additional hormonal activities in …