Intervertebral disc (IVD) degeneration is a common finding on spine imaging that increases
in prevalence with age. IVD degeneration is a frequent cause of low back pain, which is a …

Evidence from observational studies and randomized trials suggests that prediabetes and
type 2 diabetes mellitus (T2DM) can develop in genetically susceptible individuals in …

Background Type 2 diabetes mellitus (T2DM) comprises the vast majority of all diabetes
cases in adults, with alarmingly increasing prevalence over the past few decades worldwide …

Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …

Semaglutide, a glucagon like peptide-1 (GLP-1) receptor agonist, is available as
monotherapy in both subcutaneous as well as oral dosage form (first approved oral GLP-1 …

Abstract Changes in human behaviour and lifestyle over the last century have resulted in a
dramatic increase in the incidence of diabetes worldwide. The epidemic is chiefly of type 2 …

Metabolic syndrome is associated with abdominal obesity, blood lipid disorders,
inflammation, insulin resistance or full-blown diabetes, and increased risk of developing …

The Relationship between BMI and Onset of Diabetes Mellitus and its Complications - PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

Obesity and type 2 diabetes are occurring at epidemic rates in the United States and many
parts of the world. The" obesity epidemic" appears to have emerged largely from changes in …

The number of known glucose transporters has expanded considerably over the past 2
years. At least three, and up to six, Na+-dependent glucose transporters (SGLT1–SGLT6; …