Application of ultrasound for muscle assessment in sarcopenia: 2020 SARCUS update

S Perkisas, S Bastijns, S Baudry, J Bauer… - European geriatric …, 2021 - Springer
Purpose In 2018, the SARCUS working group published a first article on the standardization
of the use of ultrasound to assess muscle. Recommendations were made for patient …

Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity

KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

[HTML][HTML] Plasticity of epididymal adipose tissue in response to diet-induced obesity at single-nucleus resolution

AK Sárvári, EL Van Hauwaert, LK Markussen… - Cell metabolism, 2021 - cell.com
Adipose tissues display a remarkable ability to adapt to the dietary status. Here, we have
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …

A simple diet-and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer

T Tsuchida, YA Lee, N Fujiwara, M Ybanez, B Allen… - Journal of …, 2018 - Elsevier
Background and Aims Although the majority of patients with non-alcoholic fatty liver disease
(NAFLD) have only steatosis without progression, a sizeable fraction develop non-alcoholic …

[HTML][HTML] Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch

P Cohen, JD Levy, Y Zhang, A Frontini, DP Kolodin… - Cell, 2014 - cell.com
A clear relationship exists between visceral obesity and type 2 diabetes, whereas
subcutaneous obesity is comparatively benign. Here, we show that adipocyte-specific …

It is not just muscle mass: a review of muscle quality, composition and metabolism during ageing as determinants of muscle function and mobility in later life

RA McGregor, D Cameron-Smith, SD Poppitt - Longevity & healthspan, 2014 - Springer
Worldwide estimates predict 2 billion people will be aged over 65 years by 2050. A major
current challenge is maintaining mobility and quality of life into old age. Impaired mobility is …

Extended multiplexing of tandem mass tags (TMT) labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue

DL Plubell, PA Wilmarth, Y Zhao, AM Fenton… - Molecular & Cellular …, 2017 - ASBMB
The lack of high-throughput methods to analyze the adipose tissue protein composition
limits our understanding of the protein networks responsible for age and diet related …

Low-rank sparse subspace for spectral clustering

X Zhu, S Zhang, Y Li, J Zhang, L Yang… - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
Traditional graph clustering methods consist of two sequential steps, ie, constructing an
affinity matrix from the original data and then performing spectral clustering on the resulting …

The molecular mechanisms of obesity paradox

AS Antonopoulos, D Tousoulis - Cardiovascular research, 2017 - academic.oup.com
Clinical observations suggest a complex relationship between human obesity and
cardiovascular disease. Whilst abdominal (visceral) adiposity leads to deleterious metabolic …

Milk protein for improved metabolic health: a review of the evidence

RA McGregor, SD Poppitt - Nutrition & metabolism, 2013 - Springer
Epidemiological evidence shows that consumption of dairy products is associated with
decreased prevalence of metabolic related disorders, whilst evidence from experimental …