Orthogonal Access to α‐/β‐Branched/Linear Aliphatic Amines by Catalyst‐Tuned Regiodivergent Hydroalkylations

PF Yang, W Shu - Angewandte Chemie International Edition, 2022 - Wiley Online Library
Linear, α‐branched, and β‐branched aliphatic amines are widespread in pharmaceuticals,
agrochemicals, and fine chemicals. Thus, the development of direct and efficient methods to …

Ligand‐Controlled Nickel‐Catalyzed Regiodivergent Cross‐Electrophile Alkyl‐Alkyl Couplings of Alkyl Halides

WT Zhao, H Meng, JN Lin, W Shu - … Chemie International Edition, 2023 - Wiley Online Library
Functionalizing specific positions on a saturated alkyl molecule is a key challenge in
synthetic chemistry. Herein, a ligand‐controlled regiodivergent alkylations of alkyl bromides …

Ammonium Amphiphiles Based on Natural Compounds: Design, Synthesis, Properties, and Biomedical Applications. A Review

TN Pashirova, ZM Shaikhutdinova, VF Mironov… - Doklady Chemistry, 2023 - Springer
In order to search for new antibacterial and anticancer agents, the data of amphiphilic
quaternary ammonium compounds (QAC) based on natural structures were analyzed and …

Enantioselective and Regiodivergent Synthesis of Dihydro-1, 2-oxazines from Triene-Carbamates via Chiral Phosphoric Acid-Catalysis

E Naulin, M Lombard, V Gandon… - Journal of the …, 2023 - ACS Publications
Conjugated trienes are fascinating building blocks for the rapid construction of complex
polycyclic compounds. However, limited success has been achieved due to the challenging …

Palladium‐Catalyzed Inverse and Normal Dehydrogenative Aza‐Morita–Baylis–Hillman Reactions with γ, δ‐Unsaturated Compounds

P Chen, SZ Tan, L Zhu, Q Ouyang, ZJ Jia… - Angewandte …, 2023 - Wiley Online Library
Abstract σ‐Lewis base‐catalyzed regio‐and enantioselective aza‐Morita–Baylis–Hillman
(MBH) reaction of α, β, γ, δ‐unsaturated systems remains a challenge due to the intrinsic …

Structurally divergent enantioselective synthesis of benzofuran fused azocine derivatives and spiro-cyclopentanone benzofurans enabled by sequential catalysis

R Khuntia, SK Mahapatra, L Roy, SC Pan - Chemical Science, 2023 - pubs.rsc.org
An important objective in organic synthesis and medicinal chemistry is the capacity to
access structurally varied and complex molecules rapidly and affordably from easily …

Hydrogen Source Tuned Regiodivergent Asymmetric Hydroalkylations of 2‐Substituted 1, 3‐Dienes with Aldehydes by Cobalt‐Catalysis

XW Zeng, JN Lin, W Shu - Angewandte Chemie International …, 2024 - Wiley Online Library
Catalytic methods allowing for the reliable prediction and control of diverse regioselectivity
along with the control of enantioselectivity to access different regio‐and enantiomers by …

Regioselectivity Switch between Enantioselective 1, 2-and 1, 4-Addition of Allyl Aryl Ketones with 2, 3-Dioxopyrrolidines

BW Huang, JL Han - The Journal of Organic Chemistry, 2023 - ACS Publications
A vinylogous addition reaction of allyl aryl ketones with good yields and excellent
regioselectivity catalyzed by squaramide catalysts has been developed. A series of chiral …

Chemodivergent Sulfonylation of Enynones via Ionic and Radical Addition Modes of Sulfinic Acids

D Bhatt, HY Kim, K Oh - Organic Letters, 2023 - ACS Publications
Different addition modes of sulfinic acids were developed for the chemodivergent
sulfonylation of enynones, where the ionic sulfonylation to an alkyne moiety of enynones …

A review on solvent-controlled stereodivergent catalysis

A Kumari, A Jain, NK Rana - Tetrahedron, 2023 - Elsevier
Stereodivergent catalysis, the art of accessing multiple stereoisomers from the same starting
materials, has been a keystone of modern organic chemistry. Among the numerous factors …