A major contribution to the genome variability among individuals comes from deletions and
duplications—collectively termed copy number variations (CNVs)—which alter the diploid …

Background The presence of circulating cell-free DNA from tumours in blood (ctDNA) is of
major importance to those interested in early cancer detection, as well as to those wishing to …

Background & Aims Biomarkers are needed to risk stratify after chemoradiotherapy for
localized esophageal cancer. These could improve identification of patients at risk for cancer …

Background The recent expanding technical possibilities to detect tumor derived mutations
in blood, so-called circulating tumor DNA (ctDNA), has rapidly increased the interest in liquid …

Simple Summary The standard of care for patients diagnosed with locally advanced
esophageal cancer is neoadjuvant chemoradiotherapy followed by surgery. There is a high …

Esophageal cancer is an aggressive malignancy with a relatively poor prognosis even after
multimodality therapy. Currently, patients undergo a series of investigations that can be …

BACKGROUND: Despite the well recognized expression of the cell surface markers cluster
of differentiation 44 (homing cell adhesion molecule) and CD133 (Prominin 1) on human …

Background: VEGF is a prime mediator of tumorigenesis and metastasis. Various studies
assessing the prognostic value of VEGF in patients with esophageal cancer remain …

Esophageal squamous cell carcinoma (ESCC) is lethal as tumors are rarely detected at an
early stage and have a high recurrence rate. There are no particularly useful biomarkers for …

Gastrointestinal cancers, including oesophageal, gastric and colorectal cancers (CRC) have
high rates of disease recurrence despite curative resection. There are a number of recent …