All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

There has been an escalation in reports over the last decade examining the efficacy of bone
marrow derived mesenchymal stem/stromal cells (BMSC) in bone tissue engineering and …

Osteoarthritis (OA) is a degenerative disease resulting in irreversible, progressive
destruction of articular cartilage. The etiology of OA is complex and involves a variety of …

Adipose-derived mesenchymal stem cells (ADSCs) are promising candidate for
regenerative medicine to repair non-healing bone defects due to their high and easy …

Stem cell therapies are limited by poor cell survival and engraftment. A hurdle to the use of
materials for cell delivery is the lack of understanding of material properties that govern …

Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …

MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …

An appropriate cellular response to implanted surfaces is essential for tissue regeneration
and integration. It is well described that implanted materials are immediately coated with …

INTRODUCTION: Intracanal disinfection is a crucial step in regenerative endodontic
procedures. However, this novel endodontic treatment lacks standardization, and numerous …

There is considerable interest in the biology and therapeutic potential of adult stem cells
from bone marrow stroma, variously referred to as mesenchymal stem cells or marrow …