In recent years, microRNAs (miRNAs) have been identified as mediators of tumour
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …

The tumor suppressor p53 is one of the most frequently mutated genes in human cancers.
MicroRNAs (miRNAs) are small non-protein coding RNAs that regulate gene expression on …

During the last decade, it has become clear that aberrant microRNA expression has a
functional role in the initiation and progression of colorectal cancer (CRC). Specific …

MicroRNAs (miRNAs) are recognized as being central players in many biological processes
and cellular pathways. Their roles in disease have been highlighted first by observation of …

DNA methylation plays a key role in the silencing of numerous cancer-related genes,
thereby affecting a number of vital cellular processes, including the cell cycle checkpoint …

Cancer is a complex disease involving alterations of multiple processes, with both genetic
and epigenetic features contributing as core factors to the disease. In recent years, it has …

Purpose: MicroRNAs (miRNA) have been documented playing a critical role in cancer
development and progression. In this study, we investigate the role of miR-148a in gastric …

MicroRNAs (miRNAs) play pivotal roles in numerous biological processes, and their
dysregulation is a common feature of human cancer. Thanks to recent advances in the …

MicroRNAs (miRNAs) are highly conserved noncoding RNAs of about 19-25 nucleotides.
Through specifically pairing with complementary sites in 3'untranslated regions (UTRs) of …

miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …