[HTML][HTML] Epitope spreading: lessons from autoimmune skin diseases

LS Chan, CJ Vanderlugt, T Hashimoto… - Journal of investigative …, 1998 - Elsevier
Autoimmune diseases are initiated when patients develop aberrant T and/or B cell
responses against self proteins. These responses presumably are directed to single …

The cutaneous pathology of lupus erythematosus: a review

AN Crowson, C Magro - Journal of cutaneous pathology, 2001 - Wiley Online Library
The presentation of lupus erythematosus (LE) ranges from a skin rash unaccompanied by
extracutaneous stigmata to a rapidly progressive lethal multiorgan disease. The diagnosis …

Impact of serum cytokine levels on EEG-measured arousal regulation in patients with major depressive disorder and healthy controls

FM Schmidt, A Pschiebl, C Sander, KC Kirkby… - …, 2016 - karger.com
Background: In major depressive disorder (MDD), findings include hyperstable regulation of
brain arousal measured by electroencephalography (EEG) vigilance analysis and …

Bullous systemic lupus erythematosus

S Vassileva - Clinics in dermatology, 2004 - Elsevier
Blistering eruptions are rare cutaneous manifestations of lupus erythematosus (LE) that may
be caused by different mechanisms. Subepidermal clefting with frank vesiculation may occur …

Lichenoid dermatitis in paraneoplastic pemphigus: a pathogenic trigger of epitope spreading?

GM Bowen, NT Peters, DP Fivenson, LD Su… - Archives of …, 2000 - jamanetwork.com
Background In select cases, lichen planus has been observed to be a paraneoplastic
condition sometimes associated with paraneoplastic pemphigus, a disease featuring …

Immunobullous diseases

F Wojnarowska, VA Venning - Rook's Textbook of dermatology, 2010 - Wiley Online Library
This chapter deals with the autoimmune blistering diseases The molecular mechanisms
underpinning the structural integrity of the epidermis and its attachment to the dermis are …

Bullous lupus: an unusual initial presentation of systemic lupus erythematosus in an adolescent girl

M Tincopa, KB Puttgen, S Sule, BA Cohen… - Pediatric …, 2010 - Wiley Online Library
Bullous systemic lupus erythematosus is a subepidermal blistering disease that occurs only
rarely in a subset of patients with systemic lupus erythematosus and even less commonly in …

A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading

JA Fairley, DT Woodley, M Chen, GJ Giudice… - Journal of the American …, 2004 - Elsevier
Bullous pemphigoid (BP) and epidermolysis bullosa acquisita are distinct autoimmune
blistering disorders. BP is characterized by autoantibodies directed against the NC16A …

Immunological methods for the diagnosis of oral mucosal diseases

S Sun, B Zhong, W Li, X Jin, Y Yao… - British Journal of …, 2019 - academic.oup.com
Immunological methods, which have been widely used in autoimmune blistering diseases
(AIBDs) of the oral mucosa, can also be adopted as auxiliary diagnostic tools in oral lichen …

Autoantibodies to basement membrane proteins BP180 and BP230 are commonly detected in normal subjects by immunoblotting

N Desai, J Allen, I Ali, V Venning… - Australasian journal …, 2008 - Wiley Online Library
Autoantibodies to basement membrane proteins BP180 and BP230 are characteristic of
bullous pemphigoid and other subepidermal immunobullous disorders. These antibodies …