With the increased awareness about the importance of the composition, organization, and
stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to …

Recent data indicate that integrin and non-integrin collagen receptors cooperate in the
fibrosis-specific microenvironment (ie, the fibrotic niche). In certain tumor types, DDR1 can …

Single-molecule localization microscopy (SMLM) can reach sub-50 nm resolution using
techniques such as stochastic optical reconstruction microscopy (STORM) or DNA-point …

Physical processes ultimately shape tissue during development. Two emerging proposals
are that cells migrate toward stiffer tissue (durotaxis) and that the extent of cell …

Fibronectin (FN) is a major extracellular matrix (ECM) protein involved in a wide range of
physiological processes, including cell migration. These FN-mediated cell migration events …

Fibronectin fibrillogenesis and mechanosensing both depend on integrin-mediated force
transmission to the extracellular matrix. However, force transmission is in itself dependent on …

The cell nucleus is continuously exposed to external signals, of both chemical and
mechanical nature. To ensure proper cellular response, cells need to regulate not only the …

Abstract Single Molecule Localization Microscopy (SMLM) is a straightforward approach to
reach sub-50 nm resolution using techniques such as Stochastic Optical Reconstruction …

Within the developing embryo, cells assemble and remodel their surrounding extracellular
matrix during morphogenesis. Fibronectin is an extracellular matrix glycoprotein and is a …

Correct intestinal morphogenesis depends on the early embryonic process of gut rotation,
an evolutionarily conserved program in which a straight gut tube elongates and forms into its …