Collagen assembly at the cell surface: dogmas revisited
With the increased awareness about the importance of the composition, organization, and
stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to …
stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to …
Novel roles for cooperating collagen receptor families in fibrotic niches
C Zeltz, M Kusche-Gullberg, R Heljasvaara… - Current Opinion in Cell …, 2023 - Elsevier
Recent data indicate that integrin and non-integrin collagen receptors cooperate in the
fibrosis-specific microenvironment (ie, the fibrotic niche). In certain tumor types, DDR1 can …
fibrosis-specific microenvironment (ie, the fibrotic niche). In certain tumor types, DDR1 can …
Assessing crosstalk in simultaneous multicolor single-molecule localization microscopy
K Friedl, A Mau, F Boroni-Rueda, V Caorsi, N Bourg… - Cell Reports …, 2023 - cell.com
Single-molecule localization microscopy (SMLM) can reach sub-50 nm resolution using
techniques such as stochastic optical reconstruction microscopy (STORM) or DNA-point …
techniques such as stochastic optical reconstruction microscopy (STORM) or DNA-point …
A fibronectin gradient remodels mixed-phase mesoderm
Physical processes ultimately shape tissue during development. Two emerging proposals
are that cells migrate toward stiffer tissue (durotaxis) and that the extent of cell …
are that cells migrate toward stiffer tissue (durotaxis) and that the extent of cell …
The role of fibronectin in mediating cell migration
JH Longstreth, K Wang - American Journal of Physiology …, 2024 - journals.physiology.org
Fibronectin (FN) is a major extracellular matrix (ECM) protein involved in a wide range of
physiological processes, including cell migration. These FN-mediated cell migration events …
physiological processes, including cell migration. These FN-mediated cell migration events …
Initiation of fibronectin fibrillogenesis is an enzyme-dependent process
S Melamed, S Zaffryar-Eilot, E Nadjar-Boger, R Aviram… - Cell reports, 2023 - cell.com
Fibronectin fibrillogenesis and mechanosensing both depend on integrin-mediated force
transmission to the extracellular matrix. However, force transmission is in itself dependent on …
transmission to the extracellular matrix. However, force transmission is in itself dependent on …
[HTML][HTML] Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton
AEM Beedle, A Jaganathan, A Albajar-Sigales… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The cell nucleus is continuously exposed to external signals, of both chemical and
mechanical nature. To ensure proper cellular response, cells need to regulate not only the …
mechanical nature. To ensure proper cellular response, cells need to regulate not only the …
Robust and fast multicolor Single Molecule Localization Microscopy using spectral separation and demixing
K Friedl, A Mau, V Caorsi, N Bourg, S Lévêque-Fort… - BioRxiv, 2023 - biorxiv.org
Abstract Single Molecule Localization Microscopy (SMLM) is a straightforward approach to
reach sub-50 nm resolution using techniques such as Stochastic Optical Reconstruction …
reach sub-50 nm resolution using techniques such as Stochastic Optical Reconstruction …
Live imaging of Fibronectin 1a-mNeonGreen and Fibronectin 1b-mCherry knock-in alleles during early zebrafish development
D Jülich, SA Holley - Cells & Development, 2024 - Elsevier
Within the developing embryo, cells assemble and remodel their surrounding extracellular
matrix during morphogenesis. Fibronectin is an extracellular matrix glycoprotein and is a …
matrix during morphogenesis. Fibronectin is an extracellular matrix glycoprotein and is a …
[HTML][HTML] An atypical basement membrane forms a midline barrier in left-right asymmetric gut development
Correct intestinal morphogenesis depends on the early embryonic process of gut rotation,
an evolutionarily conserved program in which a straight gut tube elongates and forms into its …
an evolutionarily conserved program in which a straight gut tube elongates and forms into its …