Background: Conventionally, vancomycin trough levels have been used for therapeutic drug
monitoring (TDM). Owing to the increasing evidence of trough levels being poor surrogates …

Background Ototoxicity has been reported after administration of aminoglycosides and
glycopeptides. Objectives To identify available evidence for the occurrence and …

Previous data suggested several risk factors for vancomycin-induced nephrotoxicity (VIN),
including higher daily dose, long-term use, underlying renal disease, intensive care unit …

Introduction Vancomycin is a recognised cause of drug-induced acute kidney injury (AKI).
Objective The aim of this systematic review was to summarise the incidence of, and the risk …

Background Vancomycin has been widely used in the last six decades to treat methicillin-
resistant S. aureus (MRSA) and other resistant gram-positive infections. The risk of …

Purpose To comprehensively summarize the incidence and risk factors of drug-induced
kidney injury (DIKI) in children. Methods We systematically searched seven databases from …

Background: Drug-induced acute kidney injury (DIKI) is a common adverse drug reaction
event but is less known in pediatric patients. The study explored the DIKI in Chinese …

Acute kidney injury (AKI) is a commonly reported adverse effect of administration of
antimicrobials. While AKI can be associated with poorer outcomes, there is little information …

Objective To explore the efficacy and safety of vancomycin as measured by
pharmacokinetic/pharmacodynamic parameters in children with severe infection in the …

Purpose This study aims to 1) describe the distribution characteristics of teicoplanin trough
concentration (C min) and explore the related influencing factors and 2) evaluate the …