Chronic pancreatitis
J Kleeff, DC Whitcomb, T Shimosegawa… - Nature reviews Disease …, 2017 - nature.com
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the
pancreas in individuals with genetic, environmental and/or other risk factors who develop …
pancreas in individuals with genetic, environmental and/or other risk factors who develop …
Genetics, cell biology, and pathophysiology of pancreatitis
Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis,
pancreatic genetics has made rapid progress. The identification of mutations in genes …
pancreatic genetics has made rapid progress. The identification of mutations in genes …
Chronic pancreatitis
S Majumder, ST Chari - The Lancet, 2016 - thelancet.com
Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the
exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of …
exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of …
American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines
DL Conwell, LS Lee, D Yadav, DS Longnecker… - Pancreas, 2014 - journals.lww.com
The diagnosis of chronic pancreatitis remains challenging in early stages of the disease.
This report defines the diagnostic criteria useful in the assessment of patients with suspected …
This report defines the diagnostic criteria useful in the assessment of patients with suspected …
Drug-induced acute pancreatitis: a review
MR Jones, OM Hall, AM Kaye, AD Kaye - Ochsner Journal, 2015 - ochsnerjournal.org
Background The majority of drug-induced pancreatitis cases are mild to moderate in
severity, but severe and even fatal cases can occur. Management of drug-induced …
severity, but severe and even fatal cases can occur. Management of drug-induced …
Epidemiology of recurrent acute and chronic pancreatitis: similarities and differences
JD Machicado, D Yadav - Digestive diseases and sciences, 2017 - Springer
Emerging data in the past few years suggest that acute, recurrent acute (RAP), and chronic
pancreatitis (CP) represent a disease continuum. This review discusses the similarities and …
pancreatitis (CP) represent a disease continuum. This review discusses the similarities and …
Genetic risk factors for pancreatic disorders
DC Whitcomb - Gastroenterology, 2013 - Elsevier
A combination of genetic, environmental, and metabolic factors contribute to the
development and recurrence of acute and chronic pancreatitis; information on all of these is …
development and recurrence of acute and chronic pancreatitis; information on all of these is …
Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis
GA Coté, D Yadav, A Slivka, RH Hawes… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS:: Alcohol has been implicated in the development of chronic
pancreatitis (CP) in 60%–90% patients, although percentages in the United States are not …
pancreatitis (CP) in 60%–90% patients, although percentages in the United States are not …
[HTML][HTML] Genetic risk in chronic pancreatitis: the trypsin-dependent pathway
E Hegyi, M Sahin-Tóth - Digestive diseases and sciences, 2017 - Springer
Genetic investigations have provided unique insight into the mechanism of chronic
pancreatitis in humans and firmly established that uncontrolled trypsin activity is a central …
pancreatitis in humans and firmly established that uncontrolled trypsin activity is a central …
The role of alcohol and smoking in pancreatitis
D Yadav, DC Whitcomb - Nature reviews Gastroenterology & …, 2010 - nature.com
Chronic alcohol use has been linked to chronic pancreatitis for over a century, but it has not
been until the last decade that the role of alcohol in chronic pancreatitis has been elucidated …
been until the last decade that the role of alcohol in chronic pancreatitis has been elucidated …