On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and …
DB Kell, E Pretorius - Integrative Biology, 2015 - academic.oup.com
We have recently highlighted (and added to) the considerable evidence that blood can
contain dormant bacteria. By definition, such bacteria may be resuscitated (and thus …
contain dormant bacteria. By definition, such bacteria may be resuscitated (and thus …
[HTML][HTML] Individuality, phenotypic differentiation, dormancy and 'persistence'in culturable bacterial systems: commonalities shared by environmental, laboratory, and …
D Kell, M Potgieter, E Pretorius - F1000Research, 2015 - ncbi.nlm.nih.gov
For bacteria, replication mainly involves growth by binary fission. However, in a very great
many natural environments there are examples of phenotypically dormant, non-growing …
many natural environments there are examples of phenotypically dormant, non-growing …
Role of acid sphingomyelinase and IL-6 as mediators of endotoxin-induced pulmonary vascular dysfunction
R Pandolfi, B Barreira, E Moreno, V Lara-Acedo… - Thorax, 2017 - thorax.bmj.com
Background Pulmonary hypertension (PH) is frequently observed in patients with acute
respiratory distress syndrome (ARDS) and it is associated with an increased risk of mortality …
respiratory distress syndrome (ARDS) and it is associated with an increased risk of mortality …
Anti-inflammatory and anti-bacterial effects of iron chelation in experimental sepsis
S Islam, S Jarosch, J Zhou… - journal of surgical …, 2016 - Elsevier
Background Sepsis is the systemic inflammatory response to an infection. Generation of
reactive oxygen species represents an important part of the inflammatory cascade in sepsis …
reactive oxygen species represents an important part of the inflammatory cascade in sepsis …
Metabolomics and biomarkers for drug discovery
PK Yeung - Metabolites, 2018 - mdpi.com
Metabolomics and biomarkers are increasingly used in drug discovery and development,
and are applied to personalized medicine. Progress in these research areas has increased …
and are applied to personalized medicine. Progress in these research areas has increased …
Novel relationships between oxidative stress and angiogenesis-related factors in sepsis: New biomarkers and therapies
S Vera, R Martinez, JG Gormaz, A Gajardo… - Annals of …, 2015 - Taylor & Francis
Sepsis is a systemic uncontrolled inflammatory response in the presence of an infection. It
remains a major cause of morbidity and mortality in hospitalized patients. According to its …
remains a major cause of morbidity and mortality in hospitalized patients. According to its …
Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis
V Deckert, S Lemaire, PJ Ripoll, JPP de Barros… - Scientific Reports, 2017 - nature.com
Although plasma phospholipid transfer protein (PLTP) has been mainly studied in the
context of atherosclerosis, it shares homology with proteins involved in innate immunity …
context of atherosclerosis, it shares homology with proteins involved in innate immunity …
Engineered extracellular vesicles coated with an antimicrobial peptide for advanced control of bacterial sepsis
Alarming sepsis‐related mortality rates present significant challenges to healthcare services
globally. Despite advances made in the field, there is still an urgent need to develop …
globally. Despite advances made in the field, there is still an urgent need to develop …
Beneficial effects of omega-3 supplement to the enteral feeding in children with mild to moderate sepsis
MAM Al-Biltagi, AAEB Abo-Elezz… - Journal of Intensive …, 2017 - journals.sagepub.com
Objective: The objective was to investigate the benefits of supplementing enteral feeding
with omega-3 fatty acids in children with mild to moderate sepsis and its effects on acute …
with omega-3 fatty acids in children with mild to moderate sepsis and its effects on acute …
Cell-selective pore forming antimicrobial peptides of the prodomain of human furin: A conserved aromatic/cationic sequence mapping, membrane disruption, and …
Antimicrobial peptides are promising molecules in uprising consequences of drug-resistant
bacteria. The prodomain of furin, a serine protease, expressed in all vertebrates including …
bacteria. The prodomain of furin, a serine protease, expressed in all vertebrates including …