Ethnobotany and the role of plant natural products in antibiotic drug discovery
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
Unraveling plant natural chemical diversity for drug discovery purposes
E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …
benefit from the immense natural chemical diversity is a concern in many laboratories …
Natural products targeting strategies involving molecular networking: different manners, one goal
Covering: up to 2019 Landmark advances in bioinformatics tools have recently enhanced
the field of natural products research, putting today's natural product chemists in the …
the field of natural products research, putting today's natural product chemists in the …
Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities
PF Rosales, GS Bordin, AE Gower, S Moura - Fitoterapia, 2020 - Elsevier
Indole alkaloids have attracted attention because of their therapeutic properties, being anti-
inflammatory, antinociceptive, antitumoural, antioxidant and antimicrobial. These …
inflammatory, antinociceptive, antitumoural, antioxidant and antimicrobial. These …
Biosynthesis of zirconium nanoparticles (ZrO2 NPs) by Phyllanthus niruri extract: Characterization and its photocatalytic dye degradation activity
Y Yuan, Y Wu, N Suganthy, S Shanmugam… - Food and Chemical …, 2022 - Elsevier
The present study focused on microwave assisted synthesis of zirconium nanoparticles (ZrO
2 NPs) using leaf extract of Phyllanthus niruri as ecofriendly approach and assessed its …
2 NPs) using leaf extract of Phyllanthus niruri as ecofriendly approach and assessed its …
Current status and contemporary approaches to the discovery of antitumor agents from higher plants
G Agarwal, PJB Carcache, EM Addo… - Biotechnology advances, 2020 - Elsevier
Higher plant constituents have afforded clinically available anticancer drugs. These include
both chemically unmodified small molecules and their synthetic derivatives currently used or …
both chemically unmodified small molecules and their synthetic derivatives currently used or …
Feature-Based Molecular Networking Discovery of Bromopyrrole Alkaloids from the Marine Sponge Agelas dispar
VF Freire, JR Gubiani, TM Spencer… - Journal of natural …, 2022 - ACS Publications
Investigation of the marine sponge Agelas dispar MeOH fractions using feature-based
molecular networking, dereplication, and isolation led to the discovery of new bromopyrrole …
molecular networking, dereplication, and isolation led to the discovery of new bromopyrrole …
Opportunities for plant natural products in infection control
The continued spread of antimicrobial resistance represents one of the most serious
infectious disease threats to global health. There is consensus that a key component of …
infectious disease threats to global health. There is consensus that a key component of …
Targeted Isolation of Neuroprotective Dicoumaroyl Neolignans and Lignans from Sageretia theezans Using in Silico Molecular Network Annotation Propagation …
The integration of LC–MS/MS molecular networking and in silico MS/MS fragmentation is an
emerging method for dereplication of natural products. In the present study, a targeted …
emerging method for dereplication of natural products. In the present study, a targeted …
Application of feature-based molecular networking and MassQL for the MS/MS fragmentation study of depsipeptides
The Feature-based Molecular Networking (FBMN) is a well-known approach for mapping
and identifying structures and analogues. However, in the absence of prior knowledge about …
and identifying structures and analogues. However, in the absence of prior knowledge about …