Hydrogen sulfide (H2S) metabolism: Unraveling cellular regulation, disease implications, and therapeutic prospects for precision medicine

T Pandey, V Pandey - Nitric Oxide, 2024 - Elsevier
Abstract Hydrogen sulfide (H 2 S), traditionally recognized as a noxious gas with a pungent
odor, has emerged as a fascinating metabolite originating from proteinaceous foods. This …

Phenoxy-1, 2-dioxetane-based activatable chemiluminescent probes: tuning of photophysical properties for tracing enzymatic activities in living cells

JS Sidhu, G Kaur, AR Chavan, MK Chahal, R Taliyan - Analyst, 2024 - pubs.rsc.org
The use of chemiluminophores for tracing enzymatic activities in live-cell imaging has
gained significant attention, making them valuable tools for diagnostic applications. Among …

Hyper-Responsive Chemiluminescent Probe Reveals Distinct PYRase Activity in Pseudomonas aeruginosa

R Tannous, O Shelef, T Kopp, M Fridman… - Bioconjugate …, 2024 - ACS Publications
Pyrrolidone carboxyl peptidase, commonly known as PYRase, is an exopeptidase that
catalytically cleaves an N-terminal pyroglutamic acid from peptides or proteins. The diverse …

Dual-Locked Probe with Activatable Sonoafterglow Luminescence for Precise Imaging of MET-Induced Liver Injury

Z Yao, F Xu, R Wu, X Wang, M Guo, S Wang… - Analytical …, 2024 - ACS Publications
Metformin (MET) is currently the first-line treatment for type 2 diabetes mellitus (T2DM).
However, overdose and long-term use of MET may induce a serious liver injury. What's …

An activatable Near-Infrared afterglow luminescent nanoprobe with ultralong Half-Life for in vivo H2S imaging

H Zhang, C Lv, W Liu, M Yang, J Du, J Fan… - Chemical Engineering …, 2024 - Elsevier
Accurate detection of hydrogen sulfide (H 2 S) is critical for preventing and assessing the
progression of H 2 S-realted diseases; however, it remains a formidable challenge due to …

An Aggregation-Induced Fluorescence Probe for Detection H2S and Its Application in Cell Imaging

XH Tang, HN Zhang, WL Wang, QM Wang - Molecules, 2024 - mdpi.com
Monitoring hydrogen sulfide (H2S) in living organisms is very important because H2S acts
as a regulator in many physiological and pathological processes. Upregulation of …

Design and Characterization of Novel Naphthalimide Fluorescent Probe for H2S Detection in Human Serum

A Dandić, M Samardžić, M Budetić, ID Panić… - Journal of …, 2024 - Springer
In this work, a novel fluorescent probe (compound 2) based on the Intramolecular charge
transfer (ICT) mechanism was designed and successfully applied to determine H2S in …