The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE)
account for greater than 50% of the total phospholipid species in eukaryotic membranes and …

CTP: phosphocholine cytidylyltransferase (CCT) catalyzes a rate-limiting and regulated step
in the CDP-choline pathway for the synthesis of phosphatidylcholine (PC) and PC-derived …

CTP: phosphocholine cytidylyltransferase (CCT) catalyzes the synthesis of CDP-choline and
is regulatory for phosphatidylcholine biosynthesis. This review focuses on recent …

Phosphatidylcholine (PC) synthesis in animal cells is generally controlled by cytidine 5′-
triphosphate (CTP): phosphocholine cytidylyltransferase (CCT). This enzyme is amphitropic …

The CDP-ethanolamine branch of the Kennedy pathway is the major route for the formation
of ethanolamine-derived phospholipids, including diacyl phosphatidylethanolamine and …

Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in
coenzyme A (CoA) biosynthesis: the reversible adenylation of 4′-phosphopantetheine …

Phosphatidylcholine is a prominent constituent of eukaryotic and some prokaryotic
membranes. This Perspective focuses on the two enzymes that regulate its biosynthesis …

CTP phosphocholine cytidylyltransferase (CCT) is a key regulator of phosphatidylcholine
biosynthesis, and only a single isoform of this enzyme, CCTα, is known. We identified and …

ATP sulfurylases (ATPSs) are ubiquitous enzymes that catalyse the primary step of
intracellular sulfate activation: the reaction of inorganic sulfate with ATP to form adenosine …

This review explores current information on the interrelationship between phospholipid
biochemistry and cell biology. Phosphatidylcholine is the most abundant phospholipid and it …