Myelin plasticity: sculpting circuits in learning and memory

W Xin, JR Chan - Nature Reviews Neuroscience, 2020 - nature.com
Throughout our lifespan, new sensory experiences and learning continually shape our
neuronal circuits to form new memories. Plasticity at the level of synapses has been …

[HTML][HTML] Myelin in the central nervous system: structure, function, and pathology

C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Periods of synchronized myelin changes shape brain function and plasticity

O de Faria Jr, H Pivonkova, B Varga, S Timmler… - Nature …, 2021 - nature.com
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …

Cell densities in the mouse brain: a systematic review

D Keller, C Erö, H Markram - Frontiers in neuroanatomy, 2018 - frontiersin.org
The mouse brain is the most extensively studied brain of all species. We performed an
exhaustive review of the literature to establish our current state of knowledge on cell …

Myelin plasticity and nervous system function

M Monje - Annual review of neuroscience, 2018 - annualreviews.org
Structural plasticity in the myelinated infrastructure of the nervous system has come to light.
Although an innate program of myelin development proceeds independent of nervous …

Spontaneous neuronal activity in developing neocortical networks: from single cells to large-scale interactions

HJ Luhmann, A Sinning, JW Yang… - Frontiers in neural …, 2016 - frontiersin.org
Neuronal activity has been shown to be essential for the proper formation of neuronal
circuits, affecting developmental processes like neurogenesis, migration, programmed cell …

A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons

KD Micheva, D Wolman, BD Mensh, E Pax… - elife, 2016 - elifesciences.org
Myelin is best known for its role in increasing the conduction velocity and metabolic
efficiency of long-range excitatory axons. Accordingly, the myelin observed in neocortical …

Dynamics and mechanisms of CNS myelination

KK Bercury, WB Macklin - Developmental cell, 2015 - cell.com
Vertebrate myelination is an evolutionary advancement essential for motor, sensory, and
higher-order cognitive function. CNS myelin, a multilamellar differentiation of the …

Role of myelin plasticity in oscillations and synchrony of neuronal activity

S Pajevic, PJ Basser, RD Fields - Neuroscience, 2014 - Elsevier
Conduction time is typically ignored in computational models of neural network function.
Here we consider the effects of conduction delays on the synchrony of neuronal activity and …

Oligodendrocytes express synaptic proteins that modulate myelin sheath formation

AN Hughes, B Appel - Nature communications, 2019 - nature.com
Vesicular release from neurons promotes myelin sheath growth on axons. Oligodendrocytes
express proteins that allow dendrites to respond to vesicular release at synapses …