Cutaneous lupus erythematosus (CLE) is an autoimmune disease that can present as an
isolated skin disease or as a manifestation within the spectrum of systemic lupus …

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease. The disease is
characterized by activation and dysregulation of both the innate and the adaptive immune …

Cutaneous lupus erythematosus (CLE) is a common disease that may appear as a separate
entity from systemic lupus erythematosus (SLE), precede SLE development, or occur as a …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Its variable course
makes it difficult to standardize patient treatment. This article aims at a literature review on …

Abstract Acute Kidney Injury (AKI) is a major factor in sepsis-related mortality and may occur
due to lipopolysaccharide (LPS), an endotoxin produced by gram-negative bacteria that …

Objective The pathogenesis of cutaneous lupus erythematosus (CLE) is multifactorial, and
CLE is difficult to treat due to the heterogeneity of inflammatory processes among patients …

Preeclampsia (PE) is a complex pregnancy-related disorder characterized by hypertension,
followed by organ dysfunction and uteroplacental abnormalities. It remains a major cause of …

Objective: Plasmacytoid dendritic cells (pDCs) are a major source of Type-I Interferon (IFN-I),
a key driver in cutaneous lupus erythematosus (CLE). Currently evaluated in Phase II …

Although antimalarials are the primary treatment for cutaneous lupus erythematosus, not all
patients are equally responsive. We investigated whether different inflammatory cell …

Background Although existing evidence demonstrates the efficacy of antimalarials for
rheumatic skin disease, the safety of these medications, and particularly quinacrine, remains …