Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Epithelia are protected from adverse conditions by a mucous barrier. The secreted and
transmembrane mucins that constitute the mucous barrier are largely unrecognized as …

Abstract Mucin 1 (MUC1) is a heterodimeric protein formed by two subunits that is aberrantly
overexpressed in human breast cancer and other cancers. Historically, much of the early …

The introduction of technologies such as mass spectrometry and protein and DNA arrays,
combined with our understanding of the human genome, has enabled simultaneous …

Mucin-type O-glycans are a class of glycans initiated with N-acetylgalactosamine (GalNAc) α-
linked primarily to Ser/Thr residues within glycoproteins and often extended or branched by …

Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …

CA 15-3 which detects soluble forms of MUC-1 protein is the most widely used serum
marker in patients with breast cancer. Its main use is for monitoring therapy in patients with …

Publisher Summary Aberrant glycosylation is the most common phenomenon associated
with oncogenic transformation expressed in cell membranes of animal and human cancer …

We have previously demonstrated that PPARγ stimulates the terminal differentiation of
adipocyte precursors when activated by synthetic ligands, such as the antidiabetic …

The characteristics and possible functions of the most abundant proteins associated with the
bovine milk-fat globule membrane are reviewed. Under the auspices of the Milk Protein …