Chemistry and biology of ferritin
M Plays, S Müller, R Rodriguez - Metallomics, 2021 - academic.oup.com
Iron is an essential element required by cells and has been described as a key player in
ferroptosis. Ferritin operates as a fundamental iron storage protein in cells forming …
ferroptosis. Ferritin operates as a fundamental iron storage protein in cells forming …
Ferritin, cellular iron storage and regulation
Ferritin is considered the major iron storage protein which maintains a large iron core in its
cavity and has ferroxidase activity. There are many types of ferritin particularly in prokaryotes …
cavity and has ferroxidase activity. There are many types of ferritin particularly in prokaryotes …
Genetically encoded multimeric tags for subcellular protein localization in cryo-EM
Cryo-electron tomography (cryo-ET) allows for label-free high-resolution imaging of
macromolecular assemblies in their native cellular context. However, the localization of …
macromolecular assemblies in their native cellular context. However, the localization of …
Mechanisms and regulations of ferroptosis
XD Zhang, ZY Liu, MS Wang, YX Guo… - Frontiers in …, 2023 - frontiersin.org
Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis
is an iron-dependent regulated cell death whose mechanism has been extensively studied …
is an iron-dependent regulated cell death whose mechanism has been extensively studied …
Bacterial iron detoxification at the molecular level
JM Bradley, DA Svistunenko, MT Wilson… - Journal of Biological …, 2020 - ASBMB
Iron is an essential micronutrient, and, in the case of bacteria, its availability is commonly a
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …
Large protein organelles form a new iron sequestration system with high storage capacity
Iron storage proteins are essential for cellular iron homeostasis and redox balance. Ferritin
proteins are the major storage units for bioavailable forms of iron. Some organisms lack …
proteins are the major storage units for bioavailable forms of iron. Some organisms lack …
Widespread distribution of encapsulin nanocompartments reveals functional diversity
TW Giessen, PA Silver - Nature microbiology, 2017 - nature.com
Cells organize and regulate their metabolism via membrane-or protein-bound organelles. In
this way, incompatible processes can be spatially separated and controlled. In prokaryotes …
this way, incompatible processes can be spatially separated and controlled. In prokaryotes …
Encapsulins
TW Giessen - Annual review of biochemistry, 2022 - annualreviews.org
Subcellular compartmentalization is a defining feature of all cells. In prokaryotes,
compartmentalization is generally achieved via protein-based strategies. The two main …
compartmentalization is generally achieved via protein-based strategies. The two main …
Ferritin self-assembly, structure, function, and biotechnological applications
VV Sudarev, SM Dolotova, SM Bukhalovich… - International journal of …, 2023 - Elsevier
Ferritin is a vital protein complex responsible for storing iron in almost all living organisms. It
plays a crucial role in various metabolic pathways, inflammation processes, stress response …
plays a crucial role in various metabolic pathways, inflammation processes, stress response …
Structural basis for peroxidase encapsulation inside the encapsulin from the Gram-negative pathogen Klebsiella pneumoniae
JA Jones, MP Andreas, TW Giessen - Nature Communications, 2024 - nature.com
Encapsulins are self-assembling protein nanocompartments capable of selectively
encapsulating dedicated cargo proteins, including enzymes involved in iron storage, sulfur …
encapsulating dedicated cargo proteins, including enzymes involved in iron storage, sulfur …