Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review

S Nag, O Mitra, G Tripathi, S Samanta… - Immunity …, 2023 - Wiley Online Library
Background Autoimmune diseases (AD) are severe pathophysiological ailments that are
stimulated by an exaggerated immunogenic response towards self‐antigens, which can …

[HTML][HTML] The Role of MicroRNA in the Pathogenesis of Acute Kidney Injury

E Bakinowska, K Kiełbowski, A Pawlik - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Acute kidney injury (AKI) describes a condition associated with elevated serum creatinine
levels and decreased glomerular filtration rate. AKI can develop as a result of sepsis, the …

A negative regulatory role of β-cell-derived exosomes in the glucose-stimulated insulin secretion of recipient β-cells

CC Yu, CY Yang, TY Chang, KC Lan, SH Liu - Archives of Toxicology, 2024 - Springer
Exosomes are extracellular vesicles that play a role in intercellular communication through
the transportation of their cargo including mRNAs, microRNAs, proteins, and nucleic acids …

Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model

AK Elsayed, N Aldous, NM Alajez… - Stem Cell Reviews and …, 2024 - Springer
The pathogenesis of diabetes involves complex changes in the expression profiles of mRNA
and non-coding RNAs within pancreatic islet cells. Recent progress in induced pluripotent …

[HTML][HTML] Importance of Studying Non-Coding RNA in Children and Adolescents with Type 1 Diabetes

M Cabiati, G Federico, S Del Ry - Biomedicines, 2024 - mdpi.com
Type 1 diabetes (T1D) mellitus is a chronic illness in children and teens, with rising global
incidence rates. It stems from an autoimmune attack on pancreatic β cells, leading to …

[HTML][HTML] Dysfunction of PTEN-Associated MicroRNA Regulation: Exploring Potential Pathological Links in Type 1 Diabetes Mellitus

A Senyigit, S Durmus, A Oruc, R Gelisgen, H Uzun… - Medicina, 2024 - mdpi.com
Background and Objectives: Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease
with T cell-mediated pathogenesis of pancreatic β-cell destruction, leading to insulin …

MiR-375: it could be a general biomarker of metabolic changes and inflammation in type 1 diabetes patients and their siblings

EA Mostafa, NA Ismail, A El Din Abd El Baky… - Journal of …, 2024 - Springer
Purpose Type 1 diabetes (T1D) is a chronic autoimmune illness that results in loss of
pancreatic beta cells and insulin insufficiency. MicroRNAs (miRNAs) are linked to immune …