Priming of microglia with dysfunctional gut microbiota impairs hippocampal neurogenesis and fosters stress vulnerability of mice

H He, H He, L Mo, Z You, J Zhang - Brain, Behavior, and Immunity, 2024 - Elsevier
Background Mental disorders may be involved in neuroinflammatory processes that are
triggered by gut microbiota. How gut microbiota influence microglia-mediated sensitivity to …

[HTML][HTML] Alzheimer's Disease, Obesity, and Type 2 Diabetes: Focus on Common Neuroglial Dysfunctions (Critical Review and New Data on Human Brain and Models)

A Toledano, A Rodríguez-Casado, MI Älvarez… - Brain Sciences, 2024 - mdpi.com
Background/Objectives. Obesity, type 2 diabetes (T2D), and Alzheimer's disease (AD) are
pathologies that affect millions of people worldwide. They have no effective therapy and are …

Neuroimmune Activation and Microglia Reactivity in Female Rats Following Alcohol Dependence

JK Melbourne, JI Wooden, ER Carlson… - International Journal of …, 2024 - mdpi.com
The rates of alcohol use disorder among women are growing, yet little is known about how
the female brain is affected by alcohol. The neuroimmune system, and specifically microglia …

Middle-aged females are resistant to LPS-induced learning deficits: Sex comparison

LG Singleton, KF Thompson, J Carroll, RA Kohman - Neuroscience Letters, 2025 - Elsevier
Preclinical data have repeatedly shown learning and memory disruption following
administration of the bacterial endotoxin lipopolysaccharide (LPS). Normal aging is reported …

Alzheimer's Disease, Obesity, and Type 2 Diabetes: Focus on Common Neuroglial Dysfunctions (Critical Review and New Data on Human Brain and Models)

A Toledano Gasca, A Rodríguez-Casado, MI Álvarez… - 2024 - digital.csic.es
Background/Objectives. Obesity, type 2 diabetes (T2D), and Alzheimer's disease (AD) are
pathologies that affect millions of people worldwide. They have no effective therapy and are …

[PDF][PDF] The Role of the Inflammasome in Inflammaging

B Cyr - 2024 - scholarship.miami.edu
It has been established that there is an age-related increase in inflammatory molecules
during aging, leading to a chronic state of low-level inflammation known as inflammaging …

Cellular mechanisms underlying how early life stressors disrupt respiratory control

S Beyeler - 2024 - search.proquest.com
Sufficient breathing is essential to maintaining homeostatic blood gases, yet stressors early
in life undermine neural circuits controlling breathing in neonates, leading to potentially life …

Chronic intermittent ethanol exposure during adolescence produces sex-and age-dependent changes in anxiety and cognition without changes in microglia reactivity …

DB Matthews, S Scaletty, S Trapp… - Frontiers in Behavioral …, 2023 - frontiersin.org
Binge-like ethanol exposure during adolescence has been shown to produce long lasting
effects in animal models including anxiety-like behavior that can last into young adulthood …

[引用][C] Microglia and age-related cognitive decline: Primed for sex differences.

B Leuner - Brain, Behavior, and Immunity, 2023 - europepmc.org
Microglia and age-related cognitive decline: Primed for sex differences. - Abstract - Europe
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