Potential application of γ-H2AX as a biodosimetry tool for radiation triage

V Raavi, V Perumal, SFD Paul - Mutation Research/Reviews in Mutation …, 2021 - Elsevier
Radiation triage and biological dosimetry are two initial steps in the medical management of
exposed individuals following radiological accidents. Well established biodosimetry …

The hunt for radiation biomarkers: current situation

G Kultova, A Tichy, H Rehulkova… - … journal of radiation …, 2020 - Taylor & Francis
Purpose: The possibility of a large-scale acute radiation exposure necessitates the
development of new methods that could provide a rapid assessment of the doses received …

Sesamol ameliorates radiation induced DNA damage in hematopoietic system of whole body γ‐irradiated mice

A Kumar, S Choudhary, JS Adhikari… - Environmental and …, 2018 - Wiley Online Library
Ionizing radiation exposure is harmful and at high doses can lead to acute hematopoietic
radiation syndrome. Therefore, agents that can protect hematopoietic system are important …

DNA damage and gene expression changes in patients exposed to low-dose X-radiation during neuro-interventional radiology procedures

S Visweswaran, S Joseph, V Hegde… - … /Genetic Toxicology and …, 2019 - Elsevier
Interventional radiology-based imaging is the preferred choice for diagnosis and therapy of
many complex diseases, despite possible adverse effects of the radiation exposures. We …

Role of melatonin mediated G-CSF induction in hematopoietic system of gamma-irradiated mice

A Kumar, S Choudhary, S Kumar, JS Adhikari… - Life Sciences, 2022 - Elsevier
Aims Hematopoietic acute radiation syndrome (H-ARS) can cause lethality, and therefore,
the necessity of a safe radioprotector. The present study was focused on investigating the …

[HTML][HTML] Exploring the differentially expressed genes in human lymphocytes upon response to ionizing radiation: a network biology approach

TSG Sekaran, VR Kedilaya, SN Kumari… - Radiation oncology …, 2021 - ncbi.nlm.nih.gov
Purpose The integration of large-scale gene data and their functional analysis needs the
effective application of various computational tools. Here we attempted to unravel the …

Exposure of patients to low doses of X-radiation during neuro-interventional imaging and procedures: Dose estimation and analysis of γ-H2AX foci and gene …

S Visweswaran, S Joseph, J Dhanasekaran… - … /Genetic Toxicology and …, 2020 - Elsevier
Radiation has widespread applications in medicine. However, despite the benefits of
medical radiation exposures, adverse long-term health effects are cause for concern. Protein …

[HTML][HTML] Research progress on biodosimeters of ionizing radiation damage

C Xiao, N He, Y Liu, Y Wang, Q Liu - Radiation Medicine and Protection, 2020 - Elsevier
Ionizing radiation can cause radiation injury to the human body under certain circumstances,
such as unexpected radiation accidents and nuclear terrorist attacks. Methods that can …

Construction of dose response curve for 6 MV LINAC X-rays using Premature Chromosome Condensation assay for radiation dosimetry

C Meenakshi, P Venkatachalam… - Applied Radiation and …, 2021 - Elsevier
Quantification of chromosomal aberrations in the exposed personnel blood samples is
considered as a 'gold standard'and sensitive biomarker in biological dosimetry. Despite …

Hypothermia differentially modulates the formation and decay of NBS1, γH2AX and 53BP1 foci in U2OS cells exposed to gamma radiation

M Płódowska, W Krakowiak, A Węgierek-Ciuk… - Scientific Reports, 2022 - nature.com
In studies on the mechanism of DNA damage response where ionizing radiation is used as
the DNA damaging agent, cells are often exposed to ionizing radiation on melting ice …