Cadmium as a testicular toxicant: A Review

JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …

Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy

J Wang, H Zhu, K Wang, Z Yang, Z Liu - Environmental Science and …, 2020 - Springer
Cadmium (Cd), a highly toxic heavy metal, adversely affects human and animal health.
Quercetin (Que) is a kind of flavonoid that can protect many tissues from the toxic effect of …

Cadmium exposure and testis susceptibility: A systematic review in murine models

J da Silva, RV Goncalves, FCSA de Melo… - … Trace Element Research, 2021 - Springer
It is known that cadmium induces damage to the testis. However, the significant cadmium
impact on the testicular architecture and the mechanisms involved in this process are not …

Protective role of curcumin in cadmium-induced testicular injury in mice by attenuating oxidative stress via Nrf2/ARE pathway

SH Yang, JB He, LH Yu, L Li, M Long, MD Liu… - … Science and Pollution …, 2019 - Springer
The aim of the present study was to investigate whether curcumin (CUR) can ameliorate
cadmium-induced reproductive toxicity and its mechanism. A total of 48 male mice were …

Exposure to cadmium impairs sperm functions by reducing CatSper in mice

HF Wang, M Chang, TT Peng, Y Yang, N Li… - Cellular physiology and …, 2017 - karger.com
Abstract Background: Cadmium (Cd), a common environmental heavy metal and endocrine
disruptor, is known to exert toxic effects on the testes. However, the mechanisms accounting …

Altered expression of DAAM1 and PREP induced by cadmium toxicity is counteracted by melatonin in the rat testis

M Venditti, M Ben Rhouma, MZ Romano, I Messaoudi… - Genes, 2021 - mdpi.com
Cadmium (Cd) is one of the most toxic pollutants for health due to its accumulation in several
tissues, including testis. This report confirms that Cd increased oxidative stress and …

[HTML][HTML] Evidence of the protective role of D-Aspartate in counteracting/preventing cadmium-induced oxidative stress in the rat testis

M Venditti, A Santillo, D Latino, MB Rhouma… - Ecotoxicology and …, 2023 - Elsevier
Cadmium (Cd), by producing oxidative stress and acting as an endocrine disruptor, is known
to cause severe testicular injury, documented by histological and biomolecular alterations …

Bone marrow mesenchymal stem cells repair cadmium-induced rat testis injury by inhibiting mitochondrial apoptosis

YJ Wang, J Yan, XL Zou, KJ Guo, Y Zhao… - Chemico-Biological …, 2017 - Elsevier
Cadmium is a highly toxic metal with widespread exposure to people that can cause tissue
injuries that lack effective treatment. The aim of this project was to uncover whether bone …

Quercetin mediated attenuation of cadmium‐induced oxidative toxicity and apoptosis of spermatogenic cells in caprine testes in vitro

JK Bhardwaj, H Panchal - Environmental and Molecular …, 2021 - Wiley Online Library
Cadmium (Cd), an environmental toxic heavy metal, has been reported to cause testicular
toxicity, which contributes to the recent decline in male fertility worldwide. Quercetin (Qcn), a …

Mechanism of cadmium poisoning on testicular injury in mice

Y Ren, W Shao, L Zuo, WEI Zhao, H Qin… - Oncology …, 2019 - spandidos-publications.com
Cadmium is a heavy metal that is toxic to humans and the reproductive system. The present
study aimed to investigate the mechanisms of cadmium‑induced reproductive toxicity in a …