[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Amorphous solid dispersions: Rational selection of a manufacturing process

T Vasconcelos, S Marques, J das Neves… - Advanced drug delivery …, 2016 - Elsevier
Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …

An investigation into the use of polymer blends to improve the printability of and regulate drug release from pharmaceutical solid dispersions prepared via fused …

M Alhijjaj, P Belton, S Qi - European Journal of Pharmaceutics and …, 2016 - Elsevier
FDM 3D printing has been recently attracted increasing research efforts towards the
production of personalized solid oral formulations. However, commercially available FDM …

[PDF][PDF] Pharmaceutical Cocrystals: An Overview.

S Kumar, A Nanda - Indian Journal of Pharmaceutical …, 2017 - pdfs.semanticscholar.org
Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient
are the major constraints during the development of new product. Various approaches have …

Recent strategies in spray drying for the enhanced bioavailability of poorly water-soluble drugs

M Davis, G Walker - Journal of Controlled Release, 2018 - Elsevier
Poorly water-soluble drugs are a significant and ongoing issue for the pharmaceutical
industry. An overview of recent developments for the preparation of spray-dried delivery …

Pharmaceutical amorphous nanoparticles

R Jog, DJ Burgess - Journal of pharmaceutical sciences, 2017 - Elsevier
There has been a tremendous revolution in the field of nanotechnology, resulting in the
advent of novel drug delivery systems known as nanomedicines for diagnosis and therapy …

[HTML][HTML] Review–an update on the use of oral phospholipid excipients

P van Hoogevest - European journal of pharmaceutical sciences, 2017 - Elsevier
The knowledge and experiences obtained with oral phospholipid excipients is increasing
continuously. Nevertheless the present number of oral products using these excipients as …

Evolution of choice of solubility and dissolution media after two decades of biopharmaceutical classification system

N Bou-Chacra, KJC Melo, IAC Morales, ES Stippler… - The AAPS journal, 2017 - Springer
The introduction of the biopharmaceutics drug classification system (Biopharmaceutics
Classification System (BCS)), in 1995, provided a simple way to describe the …

The antisolvent coprecipitation method for enhanced bioavailability of poorly water-soluble drugs

J Zhang, M Liu, Z Zeng - International Journal of Pharmaceutics, 2022 - Elsevier
In recent years, poorly water-soluble drug candidates in the drug development pipeline have
been a challenging issue for the pharmaceutical industry. Many delivery systems, such as …

Oral bioavailability enhancement through supersaturation: an update and meta-analysis

SYK Fong, A Bauer-Brandl, M Brandl - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: With the increasing number of poorly water-soluble compounds in drug
discovery pipelines, supersaturating drug delivery systems (SDDS) have attracted increased …