Scleral structure and biomechanics
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy
Glaucoma is a complex neurodegenerative disorder that is expected to affect 80 million
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …
Simultaneous assessment of the whole eye biomechanics using ultrasonic elastography
Objective: Current elastography techniques in the field of ophthalmology usually target one
specific tissue, such as the cornea or the sclera. However, the eye is an inter-related organ …
specific tissue, such as the cornea or the sclera. However, the eye is an inter-related organ …
[HTML][HTML] TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway
Q Li, Y Cheng, S Zhang, X Sun, J Wu - Journal of neuroinflammation, 2021 - Springer
Background Glaucoma, the leading cause of irreversible blindness worldwide, is a type of
retinal disease characterized by the selective death of retinal ganglion cells (RGCs) …
retinal disease characterized by the selective death of retinal ganglion cells (RGCs) …
[HTML][HTML] Factors influencing optic nerve head biomechanics
purpose. The biomechanical environment within the optic nerve head (ONH) may play a role
in retinal ganglion cell loss in glaucomatous optic neuropathy. This was a systematic …
in retinal ganglion cell loss in glaucomatous optic neuropathy. This was a systematic …
Biomechanics of the optic nerve head
Biomechanical factors acting at the level of the lamina cribrosa (LC) are postulated to play a
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …
[HTML][HTML] Biomechanical changes in the sclera of monkey eyes exposed to chronic IOP elevations
Purpose.: To characterize scleral biomechanics in both eyes of eight monkeys in which
chronic intraocular pressure (IOP) elevation was induced in one eye. Methods.: Each …
chronic intraocular pressure (IOP) elevation was induced in one eye. Methods.: Each …
Verification, validation and sensitivity studies in computational biomechanics
Computational techniques and software for the analysis of problems in mechanics have
naturally moved from their origins in the traditional engineering disciplines to the study of …
naturally moved from their origins in the traditional engineering disciplines to the study of …
[HTML][HTML] Corneal hysteresis but not corneal thickness correlates with optic nerve surface compliance in glaucoma patients
AP Wells, DF Garway-Heath, A Poostchi… - … & visual science, 2008 - arvojournals.org
purpose. To investigate relationships between acute intraocular pressure (IOP)–induced
optic nerve head surface deformation and corneal hysteresis and thickness in glaucomatous …
optic nerve head surface deformation and corneal hysteresis and thickness in glaucomatous …
Mechanical environment of the optic nerve head in glaucoma
JC Downs, MD Roberts… - Optometry and Vision …, 2008 - journals.lww.com
The optic nerve head (ONH) is of particular interest from a biomechanical perspective
because it is a weak spot within an otherwise strong corneo-scleral envelope. The lamina …
because it is a weak spot within an otherwise strong corneo-scleral envelope. The lamina …