Super-resolution fluorescence microscopic imaging in pathogenesis and drug treatment of neurological disease

J Gong, Z Jin, H Chen, J He, Y Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Since super-resolution fluorescence microscopic technology breaks the diffraction limit that
has existed for a long time in optical imaging, it can observe the process of synapses formed …

[HTML][HTML] The role of zinc and NMDA receptors in autism spectrum disorders

K Lee, Z Mills, P Cheung, JE Cheyne, JM Montgomery - Pharmaceuticals, 2022 - mdpi.com
NMDA-type glutamate receptors are critical for synaptic plasticity in the central nervous
system. Their unique properties and age-dependent arrangement of subunit types underpin …

Glutamatergic synapse in autism: a complex story for a complex disorder

L Galineau, N Arlicot, AC Dupont, F Briend… - Molecular …, 2023 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder whose
pathophysiological mechanisms are still unclear. Hypotheses suggest a role for glutamate …

[HTML][HTML] Exposure to Antibiotics and Neurodevelopmental Disorders: Could Probiotics Modulate the Gut–Brain Axis?

T Diamanti, R Prete, N Battista, A Corsetti, A De Jaco - Antibiotics, 2022 - mdpi.com
In order to develop properly, the brain requires the intricate interconnection of genetic factors
and pre-and postnatal environmental events. The gut–brain axis has recently raised …

[HTML][HTML] Striatal increase of dopamine receptor 2 density in idiopathic and syndromic mouse models of autism spectrum disorder

S Chhabra, L Nardi, P Leukel, CJ Sommer… - Frontiers in …, 2023 - frontiersin.org
Autism spectrum disorder (ASD) comprises a wide range of neurodevelopmental
phenotypes united by impaired social interaction and repetitive behavior. Environmental and …

[HTML][HTML] Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review

NF Parrella, AT Hill, LM Dipnall, YJ Loke… - Journal of Psychiatric …, 2023 - Elsevier
The primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) has a prominent role in
regulating neural development and function, with disruption to GABAergic signalling linked …

[HTML][HTML] Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice

YX Li, ZN Tan, XH Li, B Ma, F Adu Nti, XQ Lv… - Molecular …, 2024 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
impaired social interactions, communication deficits and repetitive behaviors. A study of …

Altered synaptic protein expression, aberrant spine morphology, and impaired spatial memory in Dlgap2 mutant mice, a genetic model of autism spectrum disorder

MY Hsieh, LH Tuan, HC Chang, YC Wang… - Cerebral …, 2023 - academic.oup.com
A microdeletion of approximately 2.4 Mb at the 8p23 terminal region has been identified in a
Taiwanese autistic boy. Among the products transcribed/translated from genes mapped in …

Comparative evaluation of different chemical agents induced Autism Spectrum Disorder in experimental Wistar rats

AR Sharma, G Batra, N Dhir, A Jain, T Modi… - Behavioural Brain …, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with
uncertain etiology and pathophysiology. Several studies revealed that the commonly used …

From synapses to circuits: What mouse models have taught us about how autism spectrum disorder impacts hippocampal function

L Severino, J Kim, MH Nam, TJ McHugh - Neuroscience & Biobehavioral …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that impacts a
variety of cognitive and behavioral domains. While a genetic component of ASD has been …